Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.47 |
| ▸ | IDH1 | O75874 | 5/20 | 0.44 |
| ▸ | DDO | Q99489 | 3/20 | 0.40 |
| ▸ | FASN | P49327 | 4/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361624 | 0.76 | DAO (0.58) | DAODDO | |
| SCHEMBL3421507 | 0.76 | DAO (0.58) | DAOIDH1DDO | |
| SCHEMBL3434396 | 0.72 | DAO (0.47) | DAODDO | |
| SCHEMBL3360565 | 0.71 | DAO (0.53) | DAODDO | |
| SCHEMBL9389941 | 0.68 | UPP1 (0.34) | DAODDOFASN | |
| SCHEMBL9392754 | 0.68 | UPP1 (0.34) | DAOIDH1DDOFASN | |
| SCHEMBL9389836 | 0.67 | UPP1 (0.42) | DAOIDH1DDOFASN | |
| SCHEMBL3391789 | 0.66 | DAO (0.51) | DAOIDH1DDO | |
| SCHEMBL3393601 | 0.66 | DAO (0.51) | DAOIDH1DDO | |
| SCHEMBL25239348 | 0.65 | AHR (0.46) | GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |