Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396116 | 0.85 | MTNR1A (0.91) | MTNR1AMTNR1B | |
| SCHEMBL3398990 | 0.85 | MTNR1A (0.88) | MTNR1AMTNR1B | |
| SCHEMBL3397409 | 0.79 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL3399168 | 0.79 | MTNR1B (1.00) | MTNR1AMTNR1B | |
| SCHEMBL4981370 | 0.76 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL3979441 | 0.75 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL13135448 | 0.75 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL17066872 | 0.75 | MTNR1B (0.74) | MTNR1AMTNR1B | |
| SCHEMBL30080231 | 0.74 | MTNR1B (0.81) | MTNR1AMTNR1B | |
| SCHEMBL3397751 | 0.74 | MTNR1B (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973868-B1 | Novel elatonin ligands having antidepressant activity as well as sleep inducing properties | UNIV MCGILL (CA) | 2015-09-09 | — | — | EP | disclosed |
| US-8791163-B2 | Melatonin ligands having antidepressant activity as well as sleep inducing properties | MCGILL UNIVERSITY (CA) | 2014-07-29 | — | — | US | disclosed |
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | HCRTR1, HCRTR2, MTNR1A | MTNR1A 3/4885MTNR1B 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.