SCHEMBL339841

SCHEMBL339841

CCc1ccc(-c2ccc(CC)cc2O)c(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.73
ALDH1A1 P00352 2/20 0.48
LMNA P02545 2/20 0.48
MAPK1 P28482 2/20 0.48
RAB9A P51151 2/20 0.48
NPC1 O15118 1/20 0.48
MAPT P10636 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
CNR1 P21554 2/20 0.46
CNR2 P34972 1/20 0.46
CYP1A2 P05177 2/20 0.44
CYP2A6 P11509 1/20 0.44
POLB P06746 2/20 0.44
DAO P14920 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
PDK2 Q15119 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10770170 0.89 TRPA1 (0.59) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL19567432 0.86 TRPA1 (0.61) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL24419694 0.84 TRPA1 (0.59) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL30290839 0.84 TRPA1 (1.00) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL56556 0.84 TRPA1 (1.00) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL11017739 0.83 TRPA1 (0.57) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL29763176 0.82 TRPA1 (0.70) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL8047684 0.82 TRPA1 (0.70) TRPA1ALDH1A1LMNAMAPK1RAB9A
SCHEMBL31620174 0.80 TRPA1 (0.67) TRPA1ALDH1A1MAPK1MAPTCYP1A2
SCHEMBL1003897 0.80 TRPA1 (0.67) TRPA1ALDH1A1MAPK1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315435-B2 Method for producing hydroxyphenylcyclohexanol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-21 US disclosed
EP-2842930-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-2271651-B1 ISOTHERMAL PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-01-01 EP disclosed
EP-2346887-B1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES DOW TECHNOLOGY INVESTMENTS LLC (US) 2013-12-25 EP disclosed
US-8546600-B2 Slurry process for synthesis of bisphosphites and situ use thereof for producing bisphosphite DOW TECHNOLOGY INVESTMENTS LLC 2013-10-01 US disclosed
EP-2257560-B1 SLURRY PROCESS FOR PHOSPHOROMONOCHLORIDITE SYNTHESIS UNION CARBIDE CHEM PLASTIC (US) 2013-07-17 EP disclosed
US-8471066-B2 Slurry process for phosphoromonochloridite synthesis UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC 2013-06-25 US disclosed
US-8097749-B2 Isothermal process for phosphoromonochloridite synthesis Union Carbide Chemical and Plastics Technology Technology 2012-01-17 US disclosed
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE DOW TECHNOLOGY INVESTMENTS LLC 2011-08-11 US disclosed
EP-0323561-A2 Polyesters of bis (2-(4-hydroxyphenyl) hexafluoroisopropyl)- diphenyl ether HOECHST CELANESE CORPORATION (US) 1989-07-12 EP disclosed
US-4444960-A POLYESTER, POLYSULFONATE OCCIDENTAL CHEMICAL CORPORATION (US) 1984-04-24 US disclosed
EP-0012505-B1 GLASS FIBER-FILLED POLYBUTYLENE TEREPHTHALATE COMPOSITIONS AND MOLDED ARTICLES OF DIMINISHED WARPAGE FORMED THEREFROM OCCIDENTAL CHEMICAL CORPORATION (US) 1984-04-04 EP disclosed
US-4284549-A COMPRISING A POLYESTER OF AN AROMATIC DICARBOXYLIC ACID AND A BISPHENOL AN POLYPHENYLENE SULFIDE HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-08-18 US disclosed
US-4256625-A PERFLUOROALKENYLOXY, N-PHOSPHATOALKYL-SULFAMOYL-BENZENE SURFACTANT HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-03-17 US disclosed
US-4251429-A COMPRISING POLYPHENYLENE SULFIDE AND AN AROMATIC POLYESTER HOOKER CHEMICALS & PLASTICS CORP. (US) 1981-02-17 US disclosed
US-4211687-A AROMATIC POLYESTER, POLYPHENYLENE SULFIDE, HALO DIELS-ADER ADDUCT HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-07-08 US disclosed
US-4187259-A Polymer blends with improved hydrolytic stability comprising a linear aromatic polyester and a methacrylate cross-linked acrylate copolymer HOOKER CHEMICALS & PLASTICS CORP. (US) 1980-02-05 US disclosed
US-4137278-A TRANSESTERIFICATION CATALYST HOOKER CHEMICALS & PLASTICS CORP. (US) 1979-01-30 US disclosed
US-4126602-A THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY HOOKER CHEMICALS & PLASTICS CORP. (US) 1978-11-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150141707-A1 METHOD FOR PRODUCING HYDROXYPHENYLCYCLOHEXANOL COMPOUND HSD11B2, CYP21A2, CYP11B2 TRPA1 2672/4885ALDH1A1 905/4885LMNA 1057/4885
US-20110196166-A1 SLURRY PROCESS FOR SYNTHESIS OF BISPHOSPHITES AND SITU USE THEREOF FOR PRODUCING BISPHOSPHITE SOST, PLCB3, PPIP5K2 TRPA1 1876/4885ALDH1A1 4653/4885LMNA 3146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.