Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SLC26A4 | O43511 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL719690 | 0.90 | L3MBTL1 (0.60) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL23532065 | 0.82 | L3MBTL1 (0.57) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL9727459 | 0.81 | L3MBTL1 (0.58) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL26693543 | 0.80 | CASP3 (0.66) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL718464 | 0.79 | L3MBTL1 (0.58) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL720239 | 0.78 | CASP3 (0.70) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL717029 | 0.77 | L3MBTL1 (0.56) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL719502 | 0.77 | L3MBTL1 (0.56) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL29958563 | 0.76 | L3MBTL1 (0.65) | L3MBTL1PKMCASP3SENP8SENP7 | |
| SCHEMBL724161 | 0.76 | L3MBTL1 (0.65) | L3MBTL1PKMCASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |