Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366543 | 0.84 | TP53 (0.48) | OXTRKMT2AMEN1AVPR1AMAPT | |
| SCHEMBL3367784 | 0.82 | SMN1; SMN2 (0.37) | OXTRKMT2AKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3399462 | 0.76 | KMT2A (0.45) | OXTRKMT2ALMNAKDM4EMAPT | |
| SCHEMBL9178616 | 0.72 | KMT2A (0.62) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL6321902 | 0.67 | LMNA (0.54) | KMT2AMEN1LMNAKDM4EMAPT | |
| SCHEMBL3399452 | 0.67 | OXTR (1.00) | OXTRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL10665928 | 0.66 | LMNA (0.64) | KMT2ALMNAKDM4EMAPTTP53 | |
| SCHEMBL3364719 | 0.65 | OXTR (0.52) | OXTRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL3364725 | 0.65 | OXTR (0.52) | OXTRKMT2AMEN1LMNAKDM4E | |
| SCHEMBL5642814 | 0.65 | KMT2A (0.46) | OXTRKMT2AMEN1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |