Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399458 | 0.84 | OXTR (0.50) | TP53MAPTOXTRAVPR1ASMN1; SMN2 | |
| SCHEMBL3366546 | 0.80 | TP53 (0.49) | TP53MAPTTHRBPKMOXTR | |
| SCHEMBL3364023 | 0.74 | TRPM5 (0.44) | TP53MAPTTHRBPKMSMN1; SMN2 | |
| SCHEMBL3366536 | 0.73 | OXTR (0.74) | MAPTOXTRAVPR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3369096 | 0.73 | OXTR (0.74) | MAPTOXTRAVPR1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3367784 | 0.70 | SMN1; SMN2 (0.37) | MAPTOXTRSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL5643243 | 0.69 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1PTGER1MEN1 | |
| SCHEMBL18546039 | 0.65 | TP53 (0.69) | TP53MAPTTHRBALDH1A1HCRTR1 | |
| SCHEMBL3366540 | 0.64 | TP53 (0.56) | TP53MAPTPKMOXTRAVPR1A | |
| SCHEMBL3399462 | 0.62 | KMT2A (0.45) | TP53MAPTOXTRSMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |