Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366546 | 0.85 | TP53 (0.49) | KMT2AMAPTTP53OXTRALDH1A1 | |
| SCHEMBL3367790 | 0.81 | HDAC1 (0.41) | KMT2ALMNAHDAC1HDAC8HTT | |
| SCHEMBL3399458 | 0.76 | OXTR (0.50) | KMT2AKDM4ELMNAMAPTTP53 | |
| SCHEMBL9178616 | 0.74 | KMT2A (0.62) | KMT2AKDM4ELMNAMAPTTP53 | |
| SCHEMBL10665928 | 0.68 | LMNA (0.64) | KMT2AKDM4ELMNAMAPTTP53 | |
| SCHEMBL6321902 | 0.67 | LMNA (0.54) | KMT2AKDM4ELMNAMAPTTP53 | |
| SCHEMBL3399456 | 0.63 | OXTR (0.56) | KMT2ALMNAMAPTOXTRHTT | |
| SCHEMBL9943359 | 0.62 | PGR (0.49) | KMT2AKDM4ELMNAMAPK1HTT | |
| SCHEMBL10186889 | 0.62 | PGR (0.74) | KDM4EMAPTMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11541760 | 0.61 | PTGES2 (0.47) | KMT2AKDM4ELMNAMAPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |