Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426641 | 0.91 | HSD17B10 (0.47) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL4605053 | 0.89 | HSD17B10 (0.46) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL3118058 | 0.87 | ALDH1A1 (0.36) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL5711512 | 0.83 | HSD17B10 (0.39) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL3118165 | 0.81 | MAPT (0.50) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL3399748 | 0.80 | KMT2A (0.40) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL1457606 | 0.80 | — | — | |
| Sulfuric Acid SCHEMBL5711436 | 0.73 | ALDH1A1 (0.44) | HSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL2516919 | 0.72 | HSD17B10 (0.45) | HSD17B10ALDH1A1LMNAKDM4EMEN1 | |
| Sulfuric Acid SCHEMBL3401378 | 0.71 | KDM4E (0.35) | HSD17B10ALDH1A1LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044977-B1 | Hair dye with oxidative pre-treatment | HENKEL AG & CO KGAA (DE) | 2018-02-14 | — | — | EP | disclosed |
| EP-1944010-B1 | Brightening and/or colouring agent with acrylic acid derivative(s) | HENKEL AG & CO KGAA (DE) | 2015-03-11 | — | — | EP | disclosed |
| EP-2196184-A1 | Hair dye with colour indicator | Henkel AG & Co. KGaA (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2044977-A2 | Hair dye with oxidative pre-treatment | Henkel AG & Co. KGaA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1972323-A2 | Hair colorant | Henkel AG & Co. KGaA (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1944010-A2 | Brightening and/or colouring agent with acrylic acid derivative(s) | Henkel AG & Co. KGaA (DE) | 2008-07-16 | — | — | EP | disclosed |