SCHEMBL1426641

SCHEMBL1426641

Cc1cc(C)[n+](C)c(=O)n1CCO

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.47
ALDH1A1 P00352 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 1/20 0.37
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
POLB P06746 1/20 0.33
THRB P10828 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4605053 0.98 HSD17B10 (0.46) HSD17B10ALDH1A1LMNAMAPTKMT2A
Sulfuric Acid SCHEMBL3400219 0.91 HSD17B10 (0.41) HSD17B10ALDH1A1LMNAMAPTKMT2A
SCHEMBL3118165 0.90 MAPT (0.50) HSD17B10ALDH1A1LMNAMAPTKMT2A
SCHEMBL3118058 0.84 ALDH1A1 (0.36) HSD17B10ALDH1A1LMNAMAPTKMT2A
SCHEMBL2516919 0.79 HSD17B10 (0.45) HSD17B10ALDH1A1LMNAMAPTKMT2A
Hydrochloric Acid SCHEMBL5711289 0.78 HSD17B10 (0.44) HSD17B10ALDH1A1LMNAMAPTKMT2A
SCHEMBL1426816 0.74 KMT2A (0.46) ALDH1A1LMNAMAPTKMT2AKDM4E
SCHEMBL839103 0.72 ALOX15 (0.30)
Bromide SCHEMBL1457139 0.72 KMT2A (0.45) ALDH1A1LMNAMAPTKMT2AKDM4E
Sulfuric Acid SCHEMBL5711512 0.72 HSD17B10 (0.39) HSD17B10ALDH1A1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 EP claimed
EP-1965753-B1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO KGAA (DE) 2013-09-04 EP claimed
US-8268015-B2 Method for decolorizing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2012-09-18 US claimed
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers HENKEL AG & CO. KGAA (DE) 2011-10-13 US claimed
US-7799096-B2 Agent for dyeing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2010-09-21 US claimed
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2010-03-18 US claimed
US-7678156-B2 Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein HENKEL AG & CO. KGAA (DE) 2010-03-16 US claimed
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS HENKEL AG & CO. KGAA (DE) 2010-02-18 US claimed
EP-2018844-A2 Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds Henkel AG & Co. KGaA (DE) 2009-01-28 EP claimed
EP-2014275-A2 Kit for preparing storage-stable formulations Henkel AG & Co. KGaA (DE) 2009-01-14 EP claimed
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2008-12-11 US claimed
US-7393367-B2 Agent for dyeing keratin-based fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-07-01 US claimed
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-08 US claimed
EP-1789014-B1 SUBSTANCE FOR DYEING KERATINIC FIBERS HENKEL KGAA (DE) 2008-02-27 EP claimed
US-20070287686-A1 Substance for Dyeing Keratinic Fibers HENKEL KGAA (DE) 2007-12-13 US claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US disclosed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US disclosed
EP-1813260-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 EP disclosed
WO-2007073923-A1 HAIR COLOURANTS HENKEL AG & CO. KGAA (DE) 2007-07-05 WO disclosed
WO-2007073922-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2007-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers KRT18, PLOD3, DSG1 HSD17B10 1343/4885ALDH1A1 1067/4885LMNA 1273/4885
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS KRT18, KAT5, H1-5 HSD17B10 466/4885ALDH1A1 1093/4885LMNA 1743/4885
US-20070287686-A1 Substance for Dyeing Keratinic Fibers KRT18, SCNN1B, COL1A1 HSD17B10 419/4885ALDH1A1 210/4885LMNA 374/4885
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS KRT18, CRYAA, CKAP4 HSD17B10 703/4885ALDH1A1 426/4885LMNA 415/4885
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS KRT18, H1-10, COL1A1 HSD17B10 181/4885ALDH1A1 77/4885LMNA 1020/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO HSD17B10 322/4885ALDH1A1 111/4885LMNA 2896/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO HSD17B10 322/4885ALDH1A1 111/4885LMNA 2896/4885
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR TYR, CBR3, COXFA4L2 HSD17B10 311/4885ALDH1A1 78/4885LMNA 913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.