Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27666581 | 0.81 | APEX1 (0.32) | APEX1PTGS1AKR1C3 | |
| SCHEMBL5402343 | 0.77 | — | — | |
| SCHEMBL1865885 | 0.71 | PTGS1 (0.37) | APEX1PTGS1AKR1C3 | |
| SCHEMBL1865884 | 0.71 | PTGS1 (0.37) | APEX1PTGS1AKR1C3 | |
| SCHEMBL16543221 | 0.70 | — | — | |
| SCHEMBL4127819 | 0.70 | — | — | |
| SCHEMBL12311775 | 0.70 | — | — | |
| SCHEMBL12311770 | 0.70 | — | — | |
| SCHEMBL167103 | 0.69 | — | — | |
| SCHEMBL5998620 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323142-A1 | METHACRYLATED NANOPARTICLES AND RELATED METHOD | LI LAN (US) | 2023-10-12 | — | — | US | claimed |
| US-20230127516-A1 | REVOKING ACCESS TO A NETWORK | NCHAIN LICENSING AG (CH) | 2023-04-27 | — | — | US | claimed |
| US-8716399-B2 | Polysaccharide-grafted polyethylenimine as a gene carrier | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2014-05-06 | — | — | US | claimed |
| US-20130177976-A1 | COMBINATION OF CATIONIC POLYMERS AND POLYSACCHARIDES NANOPARTICLES AS A GENE CARRIER | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-07-11 | — | — | US | claimed |
| US-20130030119-A1 | POLYSACCHARIDE-GRAFTED POLYETHYLENIMINE AS A GENE CARRIER | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-01-31 | — | — | US | claimed |
| US-20230323142-A1 | METHACRYLATED NANOPARTICLES AND RELATED METHOD | LI LAN (US) | 2023-10-12 | — | — | US | disclosed |
| WO-2020196990-A1 | IN VITRO OSTEOARTHRITIS MODEL AND METHOD FOR SCREENING FOR OSTEOARTHRITIS TREATMENT AGENT BY USING SAME | 박동휘 | 2020-10-01 | — | — | WO | disclosed |
| US-20180223329-A1 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | UNIV JOHNS HOPKINS (US) | 2018-08-09 | — | — | US | disclosed |
| US-20160228610-A1 | TISSUE ENGINEERING USING PROGENITOR CELLS TO CATALYZE TISSUE FORMATION BY PRIMARY CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2016-08-11 | — | — | US | disclosed |
| US-20140288022-A1 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-09-25 | — | — | US | disclosed |
| US-20140219972-A1 | TISSUE ENGINEERING USING PROGENITOR CELLS TO CATALYZE TISSUE FORMATION BY PRIMARY CELLS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8742013-B2 | Synthesis of lipoamide-grafted high molecular compound and method therefor | Seoul National University of Technology Center for Industrial Collaboration (KR) | 2014-06-03 | — | — | US | disclosed |
| US-20100272761-A1 | SYNTHESIS OF LIPOAMIDE-GRAFTED HIGH MOLECULAR COMPOUND AND METHOD THEREFOR | Seoul National University of Technology Center for Industrial Collaboration (KR) | 2010-10-28 | — | — | US | disclosed |
| US-20090076606-A1 | COATED MEDICAL DEVICE | BIOMET, INC. | 2009-03-19 | — | — | US | disclosed |
| EP-1863404-A2 | COATED MEDICAL DEVICE | Cartilix, Inc. (US) | 2007-12-12 | — | — | EP | disclosed |
| US-20070098675-A1 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2007-05-03 | — | — | US | disclosed |
| EP-1558216-A4 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | UNIV JOHNS HOPKINS MED (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2006105161-A2 | COATED MEDICAL DEVICE | CARTILIX, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| EP-1558216-A2 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | Johns Hopkins University School of Medicine (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004029137-A2 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2004-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070098675-A1 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | MMP13, MMP1, MMP10 | APEX1 1541/4885PTGS1 544/4885AKR1C3 1863/4885 |
| US-20100272761-A1 | SYNTHESIS OF LIPOAMIDE-GRAFTED HIGH MOLECULAR COMPOUND AND METHOD THEREFOR | HDGF, HASPIN, LIPE | APEX1 4120/4885PTGS1 697/4885AKR1C3 3360/4885 |
| US-20180223329-A1 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | MMP13, MMP1, MMP10 | APEX1 1541/4885PTGS1 544/4885AKR1C3 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.