Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 8/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049152 | 1.00 | ANPEP (0.39) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL9390635 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL8374436 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL9394697 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL7566039 | 0.89 | ANPEP (0.37) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL8899669 | 0.87 | ANPEP (0.37) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL2465468 | 0.83 | MMP2 (0.36) | — | |
| SCHEMBL7413964 | 0.82 | ANPEP (0.39) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL7302277 | 0.77 | NPC1 (0.41) | ANPEPRNPEPDNPEPLMNAALPI | |
| SCHEMBL19922600 | 0.76 | CTSC (0.37) | ANPEPRNPEPDNPEPNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119362-A1 | Device and Method for Closure of Atrial Septal Defects | AFREMOV MICHAEL R (US) | 2017-05-04 | — | — | US | disclosed |
| US-8992567-B1 | Compressible, deformable, or deflectable tissue closure devices and method of manufacture | CARDIOVASCULAR TECHNOLOGIES INC. (US) | 2015-03-31 | — | — | US | disclosed |
| US-8518063-B2 | Arteriotomy closure devices and techniques | VASCULAR CLOSURE SYSTEMS, INC. | 2013-08-27 | — | — | US | disclosed |
| EP-2244778-A2 | DEVICE FOR CLOSURE OF ATRIAL SEPTAL DEFECTS | Afremov, Michael (US) | 2010-11-03 | — | — | EP | disclosed |
| EP-1339314-B1 | THERMO-MECHANICALLY EXPANDABLE STENT AND METHOD OF MAKING | BRAUN MEDICAL INC (US) | 2009-10-14 | — | — | EP | disclosed |
| WO-2009102831-A2 | DEVICE FOR CLOSURE OF ATRIAL SEPTAL DEFECTS | AFREMOV MICHAEL (US) | 2009-08-20 | — | — | WO | disclosed |
| US-20090209999-A1 | Device and Method for Closure of Atrial Septal Defects | AFREMOV MICHAEL | 2009-08-20 | — | — | US | disclosed |
| EP-1701671-A4 | TISSUE FASTENING SYSTEMS AND METHODS UTILIZING MAGNETIC GUIDANCE | MITRALIGN INC (US) | 2009-04-08 | — | — | EP | disclosed |
| US-20090005777-A1 | ARTERIOTOMY CLOSURE DEVICES AND TECHNIQUES | VASCULAR CLOSURE SYSTEMS, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20080114394-A1 | Arteriotomy Closure Devices and Techniques | VASCULAR CLOSURE SYSTEMS, INC. | 2008-05-15 | — | — | US | disclosed |
| US-5744457-A | ADMINISTERING HEPARIN COFACTOR II-SPECIFIC CATALYTIC AGENT | HAMILTON CIVIC HOSPITALS RESEARCH DEVELOPMENT INC. (CA) | 1998-04-28 | — | — | US | disclosed |
| WO-1998014481-A1 | PROCESSES FOR THE PREPARATION OF LOW-AFFINITY, LOW MOLECULAR WEIGHT HEPARINS USEFUL AS ANTITHROMBOTICS | HAMILTON CIVIC HOSPITALS RESEARCH DEVELOPMENT INC. (CA) | 1998-04-09 | — | — | WO | disclosed |
| US-5688507-A | Methods and compositions for inhibiting thrombogenesis | HAMILTON CIVIC HOSPITALS RESEARCH DEVELOPMENT, INC. (CA) | 1997-11-18 | — | — | US | disclosed |
| US-5670161-A | EXPANDABLE WHEN HEATED | BIOENGINEERED MATERIALS, INC. | 1997-09-23 | — | — | US | disclosed |
| WO-1996029973-A2 | COMPOSITIONS AND METHODS FOR INHIBITING THROMBOGENESIS | HAMILTON CIVIC HOSPITALS RESEARCH DEVELOPMENT INC. (CA) | 1996-10-03 | — | — | WO | disclosed |
| EP-0735050-A2 | Compositions for inhibiting thrombogenesis | HAMILTON CIVIC HOSPITALS RESEARCH DEVELOPMENT, INC. (CA) | 1996-10-02 | — | — | EP | disclosed |
| EP-0560913-A1 | BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION | BIOGEN, INC. (US) | 1993-09-22 | — | — | EP | disclosed |
| US-5242810-A | BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION | BIOGEN, INC. (US) | 1993-09-07 | — | — | US | disclosed |
| US-5240913-A | Polypeptide anticoagulants | BIOGEN, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| WO-1992010575-A1 | BIFUNCTIONAL INHIBITORS OF THROMBIN AND PLATELET ACTIVATION | BIOGEN, INC. (US) | 1992-06-25 | — | — | WO | disclosed |