Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 7/20 | 0.37 |
| ▸ | NPY1R | P25929 | 5/20 | 0.37 |
| ▸ | NPY2R | P49146 | 4/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 3/20 | 0.36 |
| ▸ | FNTB | P49356 | 3/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | MC5R | P33032 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9390635 | 1.00 | ANPEP (0.40) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL8374436 | 1.00 | ANPEP (0.40) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL7566039 | 0.95 | ANPEP (0.37) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL6049152 | 0.89 | ANPEP (0.39) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL3400148 | 0.89 | ANPEP (0.39) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL8899669 | 0.89 | ANPEP (0.37) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL2465468 | 0.89 | MMP2 (0.36) | FNTAFNTBPGGT1B | |
| SCHEMBL7302277 | 0.87 | NPC1 (0.41) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL7413964 | 0.86 | ANPEP (0.39) | ANPEPRNPEPDNPEPALPIPKM | |
| SCHEMBL11599296 | 0.83 | FOLH1 (0.38) | ANPEPRNPEPDNPEPALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994016740-A1 | THE USE OF NITRIC OXIDE-DELIVERING COMPOUNDS FOR THE TREATMENT OR PREVENTION OF ALCOHOLIC LIVER INJURY | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1994-08-04 | — | — | WO | claimed |