SCHEMBL7566039

SCHEMBL7566039

CCCN(C(=O)C(N)Cc1ccccc1)[C@H](CCCNC(=N)N)C(=O)O.O=C(CCl)CCl

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.37
RNPEP Q9H4A4 1/20 0.37
DNPEP Q9ULA0 1/20 0.37
LMNA P02545 1/20 0.36
ALPI P09923 1/20 0.36
PKM P14618 1/20 0.36
PTGS1 P23219 1/20 0.36
XIAP P98170 1/20 0.36
SLC7A5 Q01650 1/20 0.36
NPY4R P50391 8/20 0.35
NPY1R P25929 6/20 0.35
NPY2R P49146 4/20 0.35
NPY5R Q15761 4/20 0.35
FNTA P49354 3/20 0.34
FNTB P49356 3/20 0.34
PGGT1B P53609 3/20 0.34
REN P00797 1/20 0.34
LAP3 P28838 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9390635 0.95 ANPEP (0.40) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL8374436 0.95 ANPEP (0.40) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL9394697 0.95 ANPEP (0.40) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL3400148 0.89 ANPEP (0.39) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL6049152 0.89 ANPEP (0.39) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL2465468 0.88 MMP2 (0.36) FNTAFNTBPGGT1B
SCHEMBL8899669 0.87 ANPEP (0.37) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL7302277 0.83 NPC1 (0.41) ANPEPRNPEPDNPEPLMNAALPI
SCHEMBL7413964 0.82 ANPEP (0.39) ANPEPRNPEPDNPEPLMNAALPI
Arginine SCHEMBL19126740 0.80 SLC7A5 (0.52) ANPEPRNPEPDNPEPLMNAALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566245-B1 Intraluminal stent MEDTRONIC INC (US) 1999-10-06 EP claimed
US-5849034-A Intraluminal stent MEDTRONIC, INC. (US) 1998-12-15 US claimed
US-5800507-A Intraluminal stent MEDTRONIC, INC. (US) 1998-09-01 US claimed
EP-0566245-A1 Intraluminal stent MEDTRONIC, INC. (US) 1993-10-20 EP claimed
EP-0701801-B1 Method for making an intraluminal stent MEDTRONIC INC (US) 2002-08-28 EP disclosed
EP-0701802-B1 Drug eluting stent MEDTRONIC INC (US) 2002-08-28 EP disclosed
US-6399144-B2 Medical device for delivering a therapeutic substance and method therefor MEDTRONIC INC. 2002-06-04 US disclosed
EP-1208818-A2 Mold for making an intralumimal stent Medtronic Inc. (US) 2002-05-29 EP disclosed
US-20010009688-A1 Medical device for delivering a therapeutic substance and method therefor DINH THOMAS Q (US) 2001-07-26 US disclosed
US-6228845-B1 LOADING VIRUS ON FIBRIN COVERED STENT; DELIVERY OF NUCLEIC ACIDS TO CELLS MEDTRONIC, INC. 2001-05-08 US disclosed
US-6187370-B1 Medical device for delivering a therapeutic substance and method therefor MEDTRONIC, INC. 2001-02-13 US disclosed
US-6080190-A Intraluminal stent MEDTRONIC, INC. (US) 2000-06-27 US disclosed
US-5599352-A Method of making a drug eluting stent MEDTRONIC, INC. (US) 1997-02-04 US disclosed
US-5591224-A Bioelastomeric stent MEDTRONIC, INC. (US) 1997-01-07 US disclosed
US-5591227-A FIBRIN IN ADHERENT LAYER; TREATING RESTENOSIS MEDTRONIC, INC. (US) 1997-01-07 US disclosed
US-5571166-A ANTITHROMBOSIS AND ANTIRESTENOSIS PROPERTIES FOR ARTERIES FOLLOWING TRAUMA MEDTRONIC, INC. (US) 1996-11-05 US disclosed
US-5554182-A PROVIDING A STENT BODY, APPLYING FIBRINOGEN AND THROMBIN TO STENT, APPLYING HEPARIN TO FIBRINOGEN AND THROMBIN, DELIVERING STENT INTO A BODY LUMEN AND EXPANDING THE STENT MEDTRONIC, INC. (US) 1996-09-10 US disclosed
US-5510077-A POLYMERIZING FIBRINOGEN INTO FIBRIN IN FIRST MOLD CAVITY; COMPRESSING AGAINST SURFACE OF SECOND MOLD CAVITY MEDTRONIC, INC. 1996-04-23 US disclosed
EP-0701802-A1 Drug eluting stent MEDTRONIC, INC. (US) 1996-03-20 EP disclosed
EP-0566245-A1 Intraluminal stent MEDTRONIC, INC. (US) 1993-10-20 EP disclosed