Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
| ▸ | NPY4R | P50391 | 8/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | MC5R | P33032 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374436 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL9394697 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL9390635 | 0.89 | ANPEP (0.40) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL3400148 | 0.87 | ANPEP (0.39) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL6049152 | 0.87 | ANPEP (0.39) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL7566039 | 0.87 | ANPEP (0.37) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL7413964 | 0.82 | ANPEP (0.39) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL2465468 | 0.81 | MMP2 (0.36) | — | |
| SCHEMBL6674451 | 0.79 | HTT (0.34) | LMNA | |
| SCHEMBL7302277 | 0.77 | NPC1 (0.41) | ANPEPRNPEPDNPEPLMNAALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631246-A | INCREASING LEVELS OF VON WILLEBRAND FACTOR AND/OR BLOOD FACTOR VIII | THE CANADIAN RED CROSS SOCIETY (CA) | 1997-05-20 | — | — | US | disclosed |