Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2519291 | 0.90 | KDM4E (0.41) | KDM4EUSP2ALDH1A1ADORA2BADORA2A | |
| Hydrochloric Acid SCHEMBL3396465 | 0.88 | KDM4E (0.41) | KDM4EUSP2ALDH1A1ADORA2BADORA2A | |
| Sulfuric Acid SCHEMBL3399683 | 0.85 | ALDH1A1 (0.34) | KDM4EUSP2ALDH1A1LMNA | |
| Sulfuric Acid SCHEMBL5711512 | 0.83 | HSD17B10 (0.39) | KDM4EALDH1A1KMT2AMEN1HSD17B10 | |
| Sulfuric Acid SCHEMBL3397830 | 0.78 | POLB (0.39) | KDM4EALDH1A1KMT2AMEN1HTT | |
| Sulfuric Acid SCHEMBL3401490 | 0.76 | TYR (0.32) | KDM4EALDH1A1ADORA2BADORA2AKMT2A | |
| SCHEMBL2516919 | 0.73 | HSD17B10 (0.45) | KDM4EALDH1A1KMT2AMEN1GLA | |
| Hydrochloric Acid SCHEMBL5711289 | 0.72 | HSD17B10 (0.44) | KDM4EALDH1A1KMT2AMEN1HSD17B10 | |
| Sulfuric Acid SCHEMBL3400219 | 0.71 | HSD17B10 (0.41) | KDM4EALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL2524295 | 0.71 | ALDH1A1 (0.38) | KDM4EUSP2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | claimed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | claimed |
| EP-2044977-B1 | Hair dye with oxidative pre-treatment | HENKEL AG & CO KGAA (DE) | 2018-02-14 | — | — | EP | disclosed |
| EP-1944010-B1 | Brightening and/or colouring agent with acrylic acid derivative(s) | HENKEL AG & CO KGAA (DE) | 2015-03-11 | — | — | EP | disclosed |
| EP-2196184-A1 | Hair dye with colour indicator | Henkel AG & Co. KGaA (DE) | 2010-06-16 | — | — | EP | disclosed |
| EP-2044977-A2 | Hair dye with oxidative pre-treatment | Henkel AG & Co. KGaA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1972323-A2 | Hair colorant | Henkel AG & Co. KGaA (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1944010-A2 | Brightening and/or colouring agent with acrylic acid derivative(s) | Henkel AG & Co. KGaA (DE) | 2008-07-16 | — | — | EP | disclosed |
| EP-1758546-B1 | USE OF SPECIAL POLYOLS FOR INHIBITING THE CRYSTALLIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES | HENKEL KGAA (DE) | 2007-09-05 | — | — | EP | disclosed |
| EP-1800655-A1 | Use of a combination of oniumaldehydes and imidazolylalkyl-substituted p-phenylenediamine derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-06-27 | — | — | EP | disclosed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | disclosed |
| EP-1726289-A2 | Dyeing composition for keratin fibres which contains a reducing agent | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-11-29 | — | — | EP | disclosed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1433468-A1 | N-Methyl quinolinium imines used for dyeing keratin containing fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | KDM4E 577/4885USP2 3357/4885ALDH1A1 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.