Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.30 |
| ▸ | SMO | Q99835 | 2/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | CDK7 | P50613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315550 | 1.00 | CYP2A6 (0.36) | CYP2A6ABL1GCKTRPV1SMO | |
| SCHEMBL3398348 | 0.90 | CYP11B2 (0.33) | — | |
| SCHEMBL314808 | 0.90 | CYP11B2 (0.33) | — | |
| SCHEMBL315015 | 0.87 | ABL1 (0.36) | ABL1PDE10A | |
| SCHEMBL3400440 | 0.87 | ABL1 (0.36) | ABL1PDE10A | |
| SCHEMBL314163 | 0.86 | DGAT2 (0.32) | — | |
| SCHEMBL314162 | 0.86 | DGAT2 (0.32) | — | |
| SCHEMBL315650 | 0.85 | CHRNB1 (0.37) | CYP2A6ABL1 | |
| SCHEMBL315649 | 0.85 | CHRNB1 (0.37) | CYP2A6ABL1 | |
| SCHEMBL3400655 | 0.84 | CHRNB2 (0.36) | ABL1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |