Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399074 | 0.84 | — | — | |
| SCHEMBL437422 | 0.77 | PTGER4 (0.37) | PTGER4MEN1KMT2APTGER2 | |
| SCHEMBL3401329 | 0.77 | KDM4E (0.40) | PTGER4MEN1KMT2APTGER2POLB | |
| SCHEMBL15165797 | 0.77 | PTGER4 (0.35) | PTGER4MEN1KMT2APTGER2 | |
| SCHEMBL28359811 | 0.77 | LMNA (0.41) | PTGER4KMT2A | |
| SCHEMBL437373 | 0.76 | L3MBTL1 (0.40) | PTGER4MEN1KMT2APOLB | |
| SCHEMBL20550872 | 0.76 | PTGER4 (0.34) | PTGER4MEN1KMT2APTGER2 | |
| SCHEMBL20996474 | 0.76 | PTGER4 (0.34) | PTGER4MEN1KMT2APTGER2 | |
| Hydrochloric Acid SCHEMBL28753862 | 0.76 | PTGER4 (0.37) | PTGER4MEN1KMT2APTGER2 | |
| SCHEMBL15158194 | 0.73 | PTGER4 (0.37) | PTGER4MEN1KMT2APTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299463-B2 | Process for the manufacture of pyrazoles or pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2022-04-12 | — | — | US | disclosed |
| EP-3650443-A1 | CONTINUOUS FLOW SYNTHESIS OF FLUORINATED OR NON-FLUORINATED PYRAZOLES | Fujian Yongjing Technology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | FUJIAN YONGJING TECHNOLOGY CO., LTD. (CN) | 2020-05-07 | — | — | US | disclosed |
| EP-2257532-B1 | METHOD FOR REGIOSELECTIVE SYNTHESIS OF 1-ALKYL-3-HALOALKYL-1-PYRAZOL-4-CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2257532-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF L-ALKYL-3-HALOALKYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-12-08 | — | — | EP | disclosed |
| EP-2057126-B1 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-10 | — | — | EP | disclosed |
| EP-2133341-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-12-16 | — | — | EP | disclosed |
| WO-2009112157-A1 | PROCESS FOR THE REGIOSELECTIVE SYNTHESIS OF L-ALKYL-3-HALOALKYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100883-A1 | Method for regioselective synthesis of 1-alkyl-3-haloalkyl-1-pyrazol-4-carbonic acid derivatives | Bayer CropScience AG (DE) | 2009-09-16 | — | — | EP | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140390-A1 | Process for the Manufacture of Pyrazoles or Pyrimidones | DHFR, CYP4X1, CYP2F1 | PTGER4 357/4885MEN1 4644/4885KMT2A 733/4885 |
| US-11299463-B2 | Process for the manufacture of pyrazoles or pyrimidones | DHFR, CYP4X1, CYP2F1 | PTGER4 379/4885MEN1 4620/4885KMT2A 748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.