Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 6/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.35 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400129 | 0.81 | NR1H2 (0.49) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL27137149 | 0.75 | ITGB3 (0.50) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL4470355 | 0.73 | ITGB3 (0.58) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL14993623 | 0.73 | GABRP (0.39) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL30013612 | 0.73 | ITGB3 (0.48) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL27153790 | 0.73 | ITGB3 (0.48) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL23267544 | 0.72 | GBA1 (0.34) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL16415506 | 0.72 | PDK2 (0.38) | PIM1 | |
| SCHEMBL3362157 | 0.71 | NPC1 (0.42) | ITGB3ITGA2BTPSAB1TPSD1TPSG1 | |
| SCHEMBL2005065 | 0.71 | IGF2R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252613-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM, LLC (BM) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009105717-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-08-27 | — | — | WO | disclosed |