Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3396465 | 0.98 | KDM4E (0.41) | KDM4EUSP2ALDH1A1TYRPOLB | |
| Sulfuric Acid SCHEMBL3401378 | 0.90 | KDM4E (0.35) | KDM4EUSP2ALDH1A1TYRPOLB | |
| SCHEMBL2524295 | 0.79 | ALDH1A1 (0.38) | KDM4EUSP2ALDH1A1MEN1MAPT | |
| SCHEMBL2516919 | 0.78 | HSD17B10 (0.45) | KDM4EALDH1A1POLBCYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL3399040 | 0.78 | ALDH1A1 (0.37) | KDM4EUSP2ALDH1A1MEN1MAPT | |
| Hydrochloric Acid SCHEMBL5711289 | 0.77 | HSD17B10 (0.44) | KDM4EALDH1A1POLBCYP1A2HSD17B10 | |
| SCHEMBL1836068 | 0.73 | POLB (0.43) | KDM4EUSP2ALDH1A1POLBHSD17B10 | |
| Sulfuric Acid SCHEMBL5711512 | 0.71 | HSD17B10 (0.39) | KDM4EALDH1A1POLBHSD17B10MEN1 | |
| SCHEMBL2524270 | 0.70 | TYR (0.34) | ALDH1A1TYRPOLBMEN1KMT2A | |
| SCHEMBL4469156 | 0.64 | CNR2 (0.49) | KDM4EUSP2ALDH1A1POLBADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358343-B1 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO KGAA (DE) | 2016-10-19 | — | — | EP | claimed |
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | claimed |
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2011-10-13 | — | — | US | claimed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | claimed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | claimed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| EP-1796627-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2009-03-04 | — | — | EP | claimed |
| EP-2014275-A2 | Kit for preparing storage-stable formulations | Henkel AG & Co. KGaA (DE) | 2009-01-14 | — | — | EP | claimed |
| US-7473280-B2 | Coloring agent compositions and methods of treating keratin fibers therewith | HENKEL KGAA (DE) | 2009-01-06 | — | — | US | claimed |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2008-12-11 | — | — | US | claimed |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | HENKEL KGAA (DE) | 2008-08-14 | — | — | US | claimed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | claimed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | claimed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | claimed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | claimed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | disclosed |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2023-02-02 | — | — | US | disclosed |
| CN-114746069-A | Three-step multi-tone hair dyeing method | 汉高股份有限及两合公司 | 2022-07-12 | — | — | CN | disclosed |
| WO-2021110306-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2021-06-10 | — | — | WO | disclosed |
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-2044977-B1 | Hair dye with oxidative pre-treatment | HENKEL AG & CO KGAA (DE) | 2018-02-14 | — | — | EP | disclosed |
| EP-2320864-B1 | HAIR PREPARATION COMPRISING CHITOSAN SUCCINAMIDE | HENKEL AG & CO KGAA (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2358343-B1 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO KGAA (DE) | 2016-10-19 | — | — | EP | disclosed |
| EP-2026754-B1 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-1944010-B1 | Brightening and/or colouring agent with acrylic acid derivative(s) | HENKEL AG & CO KGAA (DE) | 2015-03-11 | — | — | EP | disclosed |
| EP-1965753-B1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO KGAA (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2011-10-13 | — | — | US | disclosed |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | US | disclosed |
| US-7799096-B2 | Agent for dyeing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2010-09-21 | — | — | US | disclosed |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-03-18 | — | — | US | disclosed |
| US-7678156-B2 | Compositions for treating keratinic fibers, methods of treating such fibers therewith and compounds contained therein | HENKEL AG & CO. KGAA (DE) | 2010-03-16 | — | — | US | disclosed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | HENKEL AG & CO. KGAA (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-2044977-A2 | Hair dye with oxidative pre-treatment | Henkel AG & Co. KGaA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-1796627-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2009-03-04 | — | — | EP | disclosed |
| EP-2018844-A2 | Agent for dying fibres which contain keratin comprising derivatives of naphthaldehyde in combination with CH acidic compounds | Henkel AG & Co. KGaA (DE) | 2009-01-28 | — | — | EP | disclosed |
| EP-2014275-A2 | Kit for preparing storage-stable formulations | Henkel AG & Co. KGaA (DE) | 2009-01-14 | — | — | EP | disclosed |
| US-7473280-B2 | Coloring agent compositions and methods of treating keratin fibers therewith | HENKEL KGAA (DE) | 2009-01-06 | — | — | US | disclosed |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | HENKEL AG & CO. KGAA (DE) | 2008-12-11 | — | — | US | disclosed |
| EP-1972323-A2 | Hair colorant | Henkel AG & Co. KGaA (DE) | 2008-09-24 | — | — | EP | disclosed |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | HENKEL KGAA (DE) | 2008-08-14 | — | — | US | disclosed |
| EP-1944010-A2 | Brightening and/or colouring agent with acrylic acid derivative(s) | Henkel AG & Co. KGaA (DE) | 2008-07-16 | — | — | EP | disclosed |
| US-7393367-B2 | Agent for dyeing keratin-based fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-07-01 | — | — | US | disclosed |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-08 | — | — | US | disclosed |
| EP-1917955-A2 | Performance enhanced cosmetic agent with purine and/or purine derivatives II | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1905418-A2 | Hydrogen peroxide activation with N-heterocycles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-04-02 | — | — | EP | disclosed |
| EP-1900393-A2 | Hydrogen peroxide activation with diones | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1900355-A2 | Bleaching and/or dyeing agent with heterocyclic aldehydes | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-03-19 | — | — | EP | disclosed |
| EP-1892013-A2 | Hydrogen peroxide activation with nonionic compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1891927-A2 | Hydrogen peroxide activation with methanol (hetero)aromatic compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1891930-A2 | Colour intensifying | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1789014-B1 | SUBSTANCE FOR DYEING KERATINIC FIBERS | HENKEL KGAA (DE) | 2008-02-27 | — | — | EP | disclosed |
| EP-1882495-A2 | Hydrogen peroxide activation with anionic tensides | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1882470-A2 | Hydrogen peroxide activation with betaines and/or aminoxides | Henkel Kommanditgesellschaft auf Aktien (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1880705-A2 | Brightening and/or colouring composition with improved product sensation | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-23 | — | — | EP | disclosed |
| EP-1875892-A2 | Brightening and/or dyeing agent containing pyrazoles | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-01-09 | — | — | EP | disclosed |
| EP-1870074-A2 | Brightening and/or colouring agent with anthranil acid derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1870135-A2 | Brightening and/or dyeing agent with acetamidines | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-26 | — | — | EP | disclosed |
| EP-1867320-A2 | Brightening and/or dyeing agent based on azolides | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | HENKEL KGAA (DE) | 2007-12-13 | — | — | US | disclosed |
| EP-1862198-A2 | Brightening and/or dyeing agent with urea derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-12-05 | — | — | EP | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1859783-A1 | Brightening and/or colouring agent comprising N, N'-carbonyldiazoles and/or analagogues thereof | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-1854449-A1 | Dying and/or lightening agent with cyanates | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1844762-A2 | Cosmetic medium with at least 2 silicones | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-10-17 | — | — | EP | disclosed |
| EP-1842573-A2 | Brightening and/or colouring agent with improved product sensation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-10-10 | — | — | EP | disclosed |
| EP-1825884-A2 | Brightening and/or colouring agent with reduced potential for irritation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-29 | — | — | EP | disclosed |
| EP-1813259-A2 | Bleaching and/or colouring agent with reduced potential for irritation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1813259-A2 | Bleaching and/or colouring agent with reduced potential for irritation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1813260-A2 | Bleaching and/or colouring agent with reduced potential for irritation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1813258-A2 | Bleaching and/or colouring agent with reduced potential for irritation | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1813261-A2 | Bleaching method for keratinic fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090304620-A1 | HAIR TREATMENT PRODUCTS COMPRISING POLYMERS | ASS1, SRM, COL1A1 | KDM4E 2179/4885USP2 1734/4885ALDH1A1 27/4885 |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | KRT18, PLOD3, DSG1 | KDM4E 508/4885USP2 926/4885ALDH1A1 1067/4885 |
| US-20080104772-A1 | AGENT FOR DYEING KERATIN-BASED FIBERS | KRT18, KAT5, H1-5 | KDM4E 1661/4885USP2 3976/4885ALDH1A1 1093/4885 |
| US-20070287686-A1 | Substance for Dyeing Keratinic Fibers | KRT18, SCNN1B, COL1A1 | KDM4E 615/4885USP2 4074/4885ALDH1A1 210/4885 |
| US-20100064450-A1 | AGENT FOR DYEING KERATIN-CONTAINING FIBERS | KRT18, CRYAA, CKAP4 | KDM4E 1842/4885USP2 2507/4885ALDH1A1 426/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KDM4E 1659/4885USP2 4103/4885ALDH1A1 77/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | KDM4E 1526/4885USP2 2628/4885ALDH1A1 111/4885 |
| US-20230031764-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | TYR, HAO2, HAAO | KDM4E 1526/4885USP2 2628/4885ALDH1A1 111/4885 |
| US-20080301885-A1 | REVERSIBLY CHANGEABLE HAIR COLOR | TYR, CBR3, COXFA4L2 | KDM4E 707/4885USP2 3187/4885ALDH1A1 78/4885 |
| US-20100278767-A1 | Lightening Agents and/or Dyes that Contain Aldehyde(s) | CCR3, CBR3, CCRL2 | KDM4E 3619/4885USP2 3194/4885ALDH1A1 105/4885 |
| US-20080189877-A1 | Mixture of quaternized imidazo[1,5-a]pyrimidinium derivate and benzaldehyde derivative; cationic hair dyes, oxidation color dyes; colorfastness, washfastness | TYR, NDUFS5, WASHC5 | KDM4E 1235/4885USP2 4561/4885ALDH1A1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.