Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302879 | 0.82 | OPRD1 (0.60) | SLC6A2SLC6A3OPRD1SIGMAR1HSP90AA1 | |
| SCHEMBL701917 | 0.78 | SIGMAR1 (0.35) | SLC6A2SLC6A3OPRD1SIGMAR1SLC6A4 | |
| SCHEMBL27513426 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A3OPRD1SIGMAR1HSP90AA1 | |
| SCHEMBL28598873 | 0.77 | SIGMAR1 (0.56) | SLC6A2SLC6A3OPRD1SIGMAR1SLC6A4 | |
| SCHEMBL16052071 | 0.74 | OPRD1 (0.55) | OPRD1SIGMAR1SLC6A4HSD17B10USP2 | |
| SCHEMBL27914068 | 0.74 | SIGMAR1 (0.53) | SLC6A2SLC6A3OPRD1SIGMAR1SLC6A4 | |
| SCHEMBL4869220 | 0.74 | OPRD1 (0.53) | SLC6A2SLC6A3OPRD1SIGMAR1SLC6A4 | |
| SCHEMBL14068916 | 0.74 | SLC6A3 (0.74) | SLC6A2SLC6A3HSP90AA1SLC6A4ALDH1A1 | |
| SCHEMBL10772016 | 0.73 | OPRD1 (0.57) | OPRD1SIGMAR1SLC6A4TSHROPRM1 | |
| Hydrochloric Acid SCHEMBL27492948 | 0.73 | OPRD1 (0.52) | SLC6A2SLC6A3OPRD1SIGMAR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | GRUENENTHAL GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105722-A1 | Substituted 4,5,6,7-tetrahydrothienopyridines as KCNQ2/3 Modulators | KCNQ1, KCNQ3, KCNQ2 | SLC6A2 701/4885SLC6A3 873/4885OPRD1 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.