Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 5/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.50 |
| ▸ | CHRNG | P07510 | 4/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.50 |
| ▸ | CHRND | Q07001 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27492948 | 0.98 | OPRD1 (0.52) | OPRD1SIGMAR1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL11037118 | 0.84 | SLC6A2 (0.67) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28360223 | 0.84 | SLC6A2 (0.67) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3800395 | 0.84 | ADRB2 (0.42) | OPRD1SIGMAR1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7094264 | 0.84 | OPRD1 (0.52) | OPRD1SIGMAR1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL1072701 | 0.83 | SLC6A2 (0.69) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL28057449 | 0.83 | SLC6A2 (0.65) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28598873 | 0.83 | SIGMAR1 (0.56) | OPRD1SIGMAR1SLC6A2SLC6A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22614730 | 0.83 | SLC6A2 (0.65) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL10728832 | 0.81 | SLC6A2 (0.68) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102332-B | Chalcone compound containing piperazine ring and preparation and application thereof | UNIV ZHEJIANG | 2015-05-27 | — | — | CN | claimed |
| CN-103102332-A | Chalcone compound containing piperazine ring and preparation and application thereof | UNIV ZHEJIANG | 2013-05-15 | — | — | CN | claimed |
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | claimed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | claimed |
| EP-1553092-A1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | Shanghai Institute of Pharmaceutical Industry (CN) | 2005-07-13 | — | — | EP | claimed |
| CN-1150176-C | Aralkylone pipeazine derivative and its application | �Ϻ�ҽҩ��ҵ�о�Ժ | 2004-05-19 | — | — | CN | claimed |
| CN-1381449-A | Aralkylone pipeazine derivative and its application | SHANGHAI ACADEMY OF MEDICAL IN (CN) | 2002-11-27 | — | — | CN | claimed |
| CN-1381448-A | Aralkylformylalkyl piperazine derivative and its application as brain nerve protector | SHANGHAI ACADEMY OF MEDICAL IN (CN) | 2002-11-27 | — | — | CN | claimed |
| CN-103102332-B | Chalcone compound containing piperazine ring and preparation and application thereof | UNIV ZHEJIANG | 2015-05-27 | — | — | CN | disclosed |
| CN-103102331-B | Pharmaceutical application of chalcone compound containing piperazine ring | UNIV ZHEJIANG | 2015-05-27 | — | — | CN | disclosed |
| CN-103102331-A | Pharmaceutical application of chalcone compound containing piperazine ring | UNIV ZHEJIANG | 2013-05-15 | — | — | CN | disclosed |
| CN-103102332-A | Chalcone compound containing piperazine ring and preparation and application thereof | UNIV ZHEJIANG | 2013-05-15 | — | — | CN | disclosed |
| US-7326710-B2 | Aralkyl formyl-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2008-02-05 | — | — | US | disclosed |
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2005-07-14 | — | — | US | disclosed |
| EP-1553092-A1 | ARALKYL FORMYL-ALKYL PIPERAZINE DERIVATIVES AND THEIR USES AS CEREBRAL NERVE PROTECTIVE AGENT | Shanghai Institute of Pharmaceutical Industry (CN) | 2005-07-13 | — | — | EP | disclosed |
| CN-1150176-C | Aralkylone pipeazine derivative and its application | �Ϻ�ҽҩ��ҵ�о�Ժ | 2004-05-19 | — | — | CN | disclosed |
| CN-1381449-A | Aralkylone pipeazine derivative and its application | SHANGHAI ACADEMY OF MEDICAL IN (CN) | 2002-11-27 | — | — | CN | disclosed |
| CN-1381448-A | Aralkylformylalkyl piperazine derivative and its application as brain nerve protector | SHANGHAI ACADEMY OF MEDICAL IN (CN) | 2002-11-27 | — | — | CN | disclosed |
| EP-0250193-A2 | Photoreactive lenses | GEC-MARCONI LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050153981-A1 | Aralkyl formly-alkyl piperazine derivatives and their uses as a cerebral nerve protective agent | GAP43, FABP7, AGK | OPRD1 2710/4885SIGMAR1 3862/4885CHRNB2 442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.