SCHEMBL3402020

SCHEMBL3402020

[CH]1C=CNc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34259 0.78 GAA (0.48) GAAMAPT
SCHEMBL8654087 0.76 GAA (0.46) GAAMAPT
Ammonia Solution, Strong SCHEMBL4151802 0.76 GAA (0.46) GAAMAPT
SCHEMBL29181632 0.76 GAA (0.46) GAAMAPT
Hydrochloric Acid SCHEMBL160640 0.76 GAA (0.46) GAAMAPT
Iodide SCHEMBL12466756 0.76 GAA (0.46) GAAMAPT
Water SCHEMBL16465946 0.76 GAA (0.46) GAAMAPT
Bromide SCHEMBL10654286 0.76 GAA (0.46) GAAMAPT
Water SCHEMBL4672877 0.76 GAA (0.46) GAAMAPT
SCHEMBL1787947 0.76 GAA (0.46) GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114524819-A Pesticidally active polycyclic derivatives with sulfur-containing substituents 先正达参股股份有限公司 2022-05-24 CN claimed
US-10645928-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2020-05-12 US claimed
US-10512265-B2 Pesticidally active heterocyclic derivatives with sulphur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2019-12-24 US claimed
US-10292391-B2 Pesticidally active 1,2,4-triazole derivatives with sulphur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2019-05-21 US claimed
US-20190144445-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2019-05-16 US claimed
US-10138238-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2018-11-27 US claimed
US-20180220652-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-09 US claimed
US-20180213781-A1 PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2018-08-02 US claimed
EP-3325470-A1 PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2018-05-30 EP claimed
EP-3324742-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2018-05-30 EP claimed
US-20170362224-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-12-21 US claimed
EP-3247712-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2017-11-29 EP claimed
US-20170318809-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-11-09 US claimed
EP-3214939-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Participations AG (CH) 2017-09-13 EP claimed
WO-2017016910-A1 PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-02-02 WO claimed
WO-2017016922-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2017-02-02 WO claimed
WO-2016116338-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2016-07-28 WO claimed
WO-2016071214-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2016-05-12 WO claimed
CN-114524819-A Pesticidally active polycyclic derivatives with sulfur-containing substituents 先正达参股股份有限公司 2022-05-24 CN disclosed
WO-2002069972-A2 TRIAZOLE COMPOUNDS AND THE USE THEREOF IN THE PROPHYLAXIS AND THERAPY OF NEURODEGENERATIVE DISEASES, CEREBRAL TRAUMA AND CEREBRAL ISCHEMIA ABBOTT GMBH & CO. KG (DE) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10645928-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents DDT, SQOR, ACHE GAA 3934/4885MAPT 428/4885
US-20170318809-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, SQOR, ACHE GAA 3934/4885MAPT 428/4885
US-20190144445-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, ACHE, SQOR GAA 4071/4885MAPT 487/4885
US-20170362224-A1 PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS DDT, SQOR, PTMS GAA 3771/4885MAPT 558/4885
US-20180213781-A1 PESTICIDALLY ACTIVE 1,2,4-TRIAZOLE DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS ACHE, TH, DDT GAA 3950/4885MAPT 486/4885
US-10512265-B2 Pesticidally active heterocyclic derivatives with sulphur containing substituents DDT, ACHE, GSTM1 GAA 3895/4885MAPT 661/4885
US-10292391-B2 Pesticidally active 1,2,4-triazole derivatives with sulphur containing substituents ACHE, TH, DDT GAA 3950/4885MAPT 486/4885
US-20180220652-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS DDT, ACHE, GSTM1 GAA 3895/4885MAPT 661/4885
US-10138238-B2 Pesticidally active polycyclic derivatives with sulfur containing substituents DDT, SQOR, PTMS GAA 3771/4885MAPT 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.