SCHEMBL340255

SCHEMBL340255

Cc1ccc2cccc(Br)c2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.59
BACE1 P56817 1/20 0.59
CCR1 P32246 1/20 0.58
RAB9A P51151 1/20 0.58
CCR5 P51681 1/20 0.58
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
PARP1 P09874 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
GLO1 Q04760 2/20 0.47
AR P10275 1/20 0.46
CYP1A2 P05177 1/20 0.45
NFKBIA P25963 1/20 0.43
RELA Q04206 1/20 0.43
ALDH1A1 P00352 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AGTR1 P30556 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16629769 0.86 METAP2 (0.53) METAP2BACE1CCR1RAB9ACCR5
SCHEMBL30657716 0.77 BACE1 (0.63) METAP2BACE1CCR1RAB9ACCR5
SCHEMBL339928 0.77 BACE1 (0.63) METAP2BACE1CCR1RAB9ACCR5
SCHEMBL2115749 0.77 CCR1 (0.64) METAP2CCR1RAB9ACCR5KDM4E
SCHEMBL806441 0.77 CCR1 (0.64) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL13738421 0.76 CCR1 (0.61) METAP2CCR1RAB9ACCR5KDM4E
Neocuproine SCHEMBL29639703 0.75 CCR1 (1.00) METAP2CCR1RAB9ACCR5KDM4E
Neocuproine SCHEMBL29367091 0.75 CCR1 (1.00) METAP2CCR1RAB9ACCR5KDM4E
Neocuproine SCHEMBL11672280 0.75 CCR1 (1.00) METAP2CCR1RAB9ACCR5KDM4E
Neocuproine SCHEMBL124563 0.75 CCR1 (1.00) METAP2CCR1RAB9ACCR5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113666964-B Preparation and application of thioiminoquinoline metal compound 青岛科技大学 2023-03-14 CN claimed
CN-113754583-A 2- ([2, 2' -biquinolyl ] -3-ether) -1-ethanol and derivative and synthetic method thereof 湖南工程学院 2021-12-07 CN claimed
CN-113666964-A Preparation and application of thioiminoquinoline metal compound 青岛科技大学 2021-11-19 CN claimed
CN-101602723-B Preparation method of 2-methyl-8-aminoquinoline UNIV HUNAN 2011-06-08 CN claimed
CN-101602723-A The preparation method of 2-methyl-8-quinolylamine UNIV HUNAN (CN) 2009-12-16 CN claimed
EP-4701782-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS Chevron Phillips Chemical Company LP (US) 2026-03-04 EP disclosed
EP-4701783-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES Chevron Phillips Chemical Company LP (US) 2026-03-04 EP disclosed
US-12281065-B2 Iron catalyzed highly enantioselective cis-dihydroxylation of quinones VERSITECH LIMITED (CN) 2025-04-22 US disclosed
US-20240400473-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2024-12-05 US disclosed
US-20240383894-A1 HETEROBIDENTATE IMIDAZO[1,5-A]PYRIDINE AND IMIDAZO[1,5-A]QUINOLINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME UNIV RUTGERS (US) 2024-11-21 US disclosed
WO-2024226492-A1 PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-10-31 WO disclosed
WO-2024226497-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-10-31 WO disclosed
US-6437161-B1 OLEFIN POLYMERIZATION CATALYSTS; SUBSTITUENT ON THE CYCLOPENTADIENYL RING CARRIES A DONOR FUNCTION WHICH IS BONDED RIGIDLY, NOT EXCLUSIVELY VIA SP3-HYBRIDIZED CARBON OR SILICON ATOMS, BASF AKTIENGESELLSCHAFT (DE) 2002-08-20 US disclosed
EP-1212333-A1 MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE Basell Polyolefine GmbH (DE) 2002-06-12 EP disclosed
EP-1196410-A1 RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2002-04-17 EP disclosed
WO-2001012641-A1 MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE BASELL POLYOLEFINE GMBH (DE) 2001-02-22 WO disclosed
WO-2001000615-A1 RESPIRATORY SYNCYTIAL VIRUS REPLICATION INHIBITORS JANSSEN PHARMACEUTICA N.V. (BE) 2001-01-04 WO disclosed
WO-1999041239-A1 B CELL INHIBITORS NOVARTIS AG (CH) 1999-08-19 WO disclosed
US-4530931-A 8-Quinoline carbanilates for the inhibition of lipolysis USV PHARMACEUTICAL CORP. (US) 1985-07-23 US disclosed
EP-0014929-A1 Diagnostic means, process for its preparation and its use in determining leucocytes in body fluids Roche Diagnostics GmbH (DE) 1980-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383894-A1 HETEROBIDENTATE IMIDAZO[1,5-A]PYRIDINE AND IMIDAZO[1,5-A]QUINOLINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME NDC1, NUDC, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 METAP2 4453/4885BACE1 4280/4885CCR1 1801/4885
US-12281065-B2 Iron catalyzed highly enantioselective cis-dihydroxylation of quinones NFE2L2, DUOX1, DUOX2 METAP2 2388/4885BACE1 608/4885CCR1 4491/4885
US-20240400473-A1 CATALYST SYSTEM AND ETHYLENE OLIGOMERIZATION PROCESS FOR THE PREPARATION OF LINEAR ALPHA OLEFINS AP1M1, AP2M1, OXER1 METAP2 4076/4885BACE1 1039/4885CCR1 1082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.