SCHEMBL475824

SCHEMBL475824

CC(=O)O[Si](c1ccc(C)cc1)(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.48
ALDH1A1 P00352 6/20 0.39
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
TDP1 Q9NUW8 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
PKM P14618 2/20 0.35
HTT P42858 2/20 0.35
ATM Q13315 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HPGD P15428 1/20 0.35
NLRP1 Q9C000 1/20 0.35
GAA P10253 1/20 0.35
MEN1 O00255 1/20 0.35
NTSR1 P30989 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
STAT3 P40763 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL704476 0.83 CES2 (0.41) ALDH1A1CES2CES1TDP1SMN1; SMN2
SCHEMBL6562707 0.83 LMNA (0.48) LMNAALDH1A1CES2CES1TDP1
SCHEMBL6884399 0.82 LMNA (0.39) LMNAALDH1A1CES2CES1TDP1
SCHEMBL475950 0.81 LMNA (0.47) LMNAALDH1A1CES2CES1TDP1
SCHEMBL476126 0.80 CES2 (0.43) ALDH1A1CES2CES1TDP1SMN1; SMN2
SCHEMBL4643859 0.78 CYP2C19 (0.36) LMNAALDH1A1CES2CES1TDP1
SCHEMBL14062436 0.78 LMNA (0.44) LMNAALDH1A1CES2CES1TDP1
SCHEMBL4643590 0.76 CYP2C19 (0.35) LMNAALDH1A1CES2CES1TDP1
SCHEMBL4647347 0.76 ALDH1A1 (0.36) LMNAALDH1A1CES2CES1TDP1
SCHEMBL4644558 0.75 L3MBTL1 (0.36) LMNAALDH1A1CES2CES1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2912120-B1 ANTIFOULING COATING COMPOSITION JOTUN AS (NO) 2017-12-20 EP disclosed
EP-2725073-B1 Antifouling coating composition JOTUN AS (NO) 2016-08-03 EP disclosed
EP-2912120-A1 ANTIFOULING COATING COMPOSITION Jotun A/S (NO) 2015-09-02 EP disclosed
WO-2014064048-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
WO-2014064049-A1 ANTIFOULING COATING COMPOSITION JOTUN A/S (NO) 2014-05-01 WO disclosed
EP-2725073-A1 Antifouling coating composition Jotun A/S (NO) 2014-04-30 EP disclosed
EP-2708594-A1 Cleaning process Jotun A/S (NO) 2014-03-19 EP disclosed
EP-2348077-B1 Antifouling composition JOTUN AS (NO) 2013-04-03 EP disclosed
EP-2173780-B1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN AS (NO) 2012-05-23 EP disclosed
EP-2294148-B1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN AS (NO) 2012-02-01 EP disclosed
WO-2011092143-A1 ANTIFOULING COMPOSITION JOTUN A/S (NO) 2011-08-04 WO disclosed
EP-2348077-A1 Antifouling composition Jotun A/S (NO) 2011-07-27 EP disclosed
US-20110123478-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2011-05-26 US disclosed
EP-2294148-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER Jotun A/S (NO) 2011-03-16 EP disclosed
EP-2173780-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER Jotun A/S (NO) 2010-04-14 EP disclosed
WO-2009149919-A1 BINDER FOR ANTIFOULING COATING COMPOSITION AND ANTIFOULING COATING COMPOSITION COMPRISING BINDER JOTUN A/S (NO) 2009-12-17 WO disclosed
WO-2009007276-A1 BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER JOTUN A/S (NO) 2009-01-15 WO disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
WO-2004005302-A1 PROCESS FOR THE PREPARATION OF ACYLOXYSILANES SIGMA COATINGS B.V. (NL) 2004-01-15 WO disclosed
EP-1378514-A1 Process for the preparation of acyloxysilanes SigmaKalon Group B.V. (NL) 2004-01-07 EP disclosed