Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | FADS1 | O60427 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407763 | 0.86 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDMAPK1MAPT | |
| SCHEMBL3404051 | 0.82 | EGFR (0.48) | HPGDMAPTKMT2AFADS1MEN1 | |
| SCHEMBL3409035 | 0.80 | MAPT (0.44) | ALDH1A1CYP3A4HPGDMAPTKMT2A | |
| SCHEMBL154556 | 0.75 | NPC1 (0.46) | KMT2ARAB9ANPC1MEN1 | |
| SCHEMBL154554 | 0.74 | SLC5A2 (0.36) | CYP3A4RAB9ANPC1MAPK8 | |
| SCHEMBL3409107 | 0.74 | GAA (0.44) | ALDH1A1MAPTKMT2AMAPK8 | |
| SCHEMBL3406738 | 0.72 | KCNMA1 (0.46) | ALDH1A1HPGDMAPK1MAPTKMT2A | |
| SCHEMBL3402632 | 0.68 | HTT (0.45) | ALDH1A1HPGDMAPK1MAPTKMT2A | |
| SCHEMBL28693273 | 0.67 | MTNR1A (0.49) | ALDH1A1CYP3A4HPGDMAPK1MAPT | |
| Paeonol SCHEMBL1449478 | 0.67 | HPGD (1.00) | ALDH1A1CYP3A4HPGDMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |