Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788227 | 0.89 | GSK3B (0.42) | GSK3BHTR4CYP1A2CYP2D6HTR3A | |
| SCHEMBL3400823 | 0.84 | HTR4 (0.42) | HTR4CYP1A2CYP2D6ADRA2CACHE | |
| SCHEMBL3398498 | 0.81 | GSK3B (0.38) | GSK3BCYP1A2CYP2D6CNR1CNR2 | |
| SCHEMBL3399684 | 0.79 | CRBN (0.42) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL927355 | 0.79 | GSK3B (0.39) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL3425658 | 0.79 | KCNMA1 (0.40) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL3399648 | 0.79 | KDM4E (0.43) | GSK3BCYP1A2CYP2D6CNR1CNR2 | |
| SCHEMBL3402173 | 0.78 | GSK3B (0.45) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL3400870 | 0.77 | GSK3B (0.42) | GSK3BCYP1A2CYP2D6 | |
| SCHEMBL3401042 | 0.77 | GSK3B (0.39) | GSK3BCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247598-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-11-10 | — | — | EP | claimed |
| WO-2009095787-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | claimed |
| EP-2247598-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009095787-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | disclosed |