Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 6/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404997 | 0.82 | NPFFR1 (0.41) | ADRB2ALDH1A1HTTNPFFR1NPFFR2 | |
| SCHEMBL3410176 | 0.72 | DPP4 (0.38) | — | |
| SCHEMBL7015711 | 0.69 | CTSS (0.51) | ADRB2ALDH1A1HTTCA1CA2 | |
| SCHEMBL3407709 | 0.67 | SIGMAR1 (0.40) | CETPALDH1A1 | |
| SCHEMBL3404994 | 0.65 | CYP1A2 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL18426282 | 0.65 | MME (0.38) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3410556 | 0.63 | CYP1A2 (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27750414 | 0.63 | HPGD (0.38) | CETPALDH1A1 | |
| SCHEMBL1736885 | 0.62 | ALDH1A1 (0.64) | ALDH1A1CA1CA2KMT2AL3MBTL1 | |
| SCHEMBL6540719 | 0.61 | ADRB2 (0.45) | ADRB2ALDH1A1HTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197851-A1 | DERIVATIVES OF N-PHENYLACETAMIDE AS INHIBITORS OF THE ENZYME SOAT1 FOR PHARMACEUTICAL AND COSMETIC USE | Galderma Research & Development (FR) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030750-A1 | DERIVATIVES OF N-PHENYLACETAMIDE AS INHIBITORS OF THE ENZYME SOAT1 FOR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-03-12 | — | — | WO | disclosed |