Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405569 | 0.91 | CNR1 (0.48) | CNR1HTR2CMAPTTHRATHRB | |
| SCHEMBL3405771 | 0.91 | CNR1 (0.43) | TRPM8CNR1HTR2CTHRATHRB | |
| SCHEMBL3402239 | 0.89 | CNR1 (0.49) | CNR1HTR2CTHRATHRBCES2 | |
| SCHEMBL3405405 | 0.89 | KMT2A (0.53) | TRPM8CNR1HTR2CMAPTTHRA | |
| SCHEMBL3405660 | 0.89 | THRA (0.45) | TRPM8CNR1HTR2CMAPTTHRA | |
| SCHEMBL3402581 | 0.89 | CNR1 (0.47) | TRPM8CNR1HTR2CMAPTTHRA | |
| SCHEMBL3401176 | 0.89 | CNR1 (0.60) | CNR1HTR2CMAPTCES2HRH3 | |
| SCHEMBL3403910 | 0.89 | ALDH1A1 (0.55) | CNR1HTR2CMAPTTHRATHRB | |
| SCHEMBL3405411 | 0.88 | CNR1 (0.46) | CNR1HTR2CMAPTTHRATHRB | |
| SCHEMBL3402322 | 0.88 | CNR1 (0.46) | CNR1HTR2CMAPTTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |