Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065663 | 0.79 | MAPT (0.74) | POLBALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL3410102 | 0.77 | LMNA (0.51) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3412404 | 0.77 | ALDH1A1 (0.74) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16299041 | 0.75 | MAPT (0.57) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL3409542 | 0.75 | MAPT (0.50) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL1242644 | 0.74 | MAPT (0.43) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL16763191 | 0.73 | GAA (0.50) | ALDH1A1MAPTSMN1; SMN2KDM4ETDP1 | |
| SCHEMBL10144038 | 0.72 | MEN1 (0.55) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL3412013 | 0.72 | MAPT (0.58) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL30691806 | 0.72 | HDAC1 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | CHROMOCELL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2011130707-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011130707-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | TAS2R5, TAS2R20, TAS2R10 | POLB 4854/4885ALDH1A1 1771/4885MAPT 4340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.