Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.41 |
| ▸ | RXRB | P28702 | 9/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.41 |
| ▸ | RXRG | P48443 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31411073 | 0.84 | BTN3A1 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL3722014 | 0.81 | RXRA (0.51) | RXRARXRBNR4A2RXRGALDH1A1 | |
| SCHEMBL1628200 | 0.80 | TBXAS1 (0.41) | RXRARXRBNR4A2RXRGALDH1A1 | |
| SCHEMBL4741957 | 0.78 | ALDH1A1 (0.44) | RXRARXRBNR4A2RXRGALDH1A1 | |
| SCHEMBL27032528 | 0.77 | DUT (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL27131617 | 0.77 | DUT (0.37) | ALDH1A1MAPK1 | |
| SCHEMBL4197217 | 0.73 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1749434 | 0.73 | ALDH1A1 (0.53) | RXRARXRBNR4A2RXRGALDH1A1 | |
| SCHEMBL20427410 | 0.72 | RARB (0.52) | RXRARXRBALDH1A1TP53 | |
| SCHEMBL6937584 | 0.72 | HTT (0.40) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257315-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | Lantheus Medical Imaging, Inc. (US) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009110984-A2 | CONTRAST AGENTS FOR APPLICATIONS INCLUDING PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-1713512-A4 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2009-01-07 | — | — | EP | disclosed |
| EP-1713512-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | Bristol-Myers Squibb Pharma Company (US) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005079391-A2 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |