Sulfuric Acid

Sulfuric Acid

SCHEMBL340576

O=S(=O)(O)O.OCCO.[KH]

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA5A P35218 2/20 0.55
CA5B Q9Y2D0 2/20 0.55
TSHR P16473 4/20 0.46
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
NT5E P21589 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BLM P54132 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
PTGS1 P23219 1/20 0.32
PDE4A P27815 1/20 0.32
TP53 P04637 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL28791682 0.95 CA5A (0.60) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL921114 0.95 CA5A (0.60) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL126226 0.95
Sulfuric Acid SCHEMBL3280249 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL924013 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL2313307 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL28463255 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL2302635 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL21635099 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL4529065 0.91 CA5A (0.55) CA5ACA5BTSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916487-A Peptide composition and uses thereof 米尼翁大学 2016-08-31 CN disclosed
US-8097602-B1 Method of treating body insect infestation HOST PHARMACEUTICALS, LLC (US) 2012-01-17 US disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
WO-2009105617-A1 METHOD OF TREATING BODY INSECT INFESTATION HOST PHARMACEUTICALS, LLC (US) 2009-08-27 WO disclosed
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. 2009-03-12 US disclosed
WO-2008134712-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. (US) 2008-11-06 WO disclosed
US-RE40534-E1 Clear conditioning detersive compositions containing polysiloxanes with at least one cyclic side chain CHEMSIL SILICONES, INC. (US) 2008-10-07 US disclosed
US-6642194-B2 Clear hair shampoo composition comprising detersive component, emulsifier component and polysiloxane component in amount effective as hair conditioner CHEMSIL SILICONES, INC. 2003-11-04 US disclosed
US-6605577-B1 Having a hindered amine group; hair shampoo CHEMSIL SILICONES, INC. 2003-08-12 US disclosed
US-20030134760-A1 Clear conditioning detersive compositions and methods for making the same CHEMSIL SILICONES, INC. 2003-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE MMP1, MMP9, MMP17 CA5A 1314/4885CA5B 1071/4885TSHR 2597/4885
US-20030134760-A1 Clear conditioning detersive compositions and methods for making the same ASH2L, CD47, THOC2 CA5A 2170/4885CA5B 2529/4885TSHR 3839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.