Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405645 | 0.84 | ABHD6 (0.30) | DYRK3CLK1CLK2CLK3GSK3A | |
| SCHEMBL3410002 | 0.75 | IRAK4 (0.35) | IRAK4KDM4ENPC1RAB9AHKDC1 | |
| SCHEMBL3410313 | 0.75 | NPC1 (0.46) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL3407756 | 0.74 | SMPD1 (0.34) | NPC1RAB9A | |
| SCHEMBL3407555 | 0.66 | MAPT (0.32) | — | |
| SCHEMBL3402152 | 0.65 | NAALAD2 (0.37) | — | |
| SCHEMBL22445787 | 0.64 | KDM4E (0.46) | KDM4ENPC1RAB9AHKDC1TDP1 | |
| SCHEMBL2869557 | 0.64 | GFER (0.40) | DYRK3CLK1CLK2CLK3GSK3B | |
| SCHEMBL25142297 | 0.63 | DYRK3 (0.32) | DYRK3CLK1CLK2CLK3GSK3A | |
| SCHEMBL25804749 | 0.63 | RAB9A (0.38) | IRAK4KDM4ENPC1RAB9AHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |