Methane

Methane

SCHEMBL3409043

C.O.[C]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Methane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL6261812 1.00
Methane SCHEMBL1193503 0.87
Methane SCHEMBL1849066 0.87
Methane SCHEMBL8673546 0.87
Methane SCHEMBL23877922 0.82
Water SCHEMBL11650413 0.82
Methane SCHEMBL4455396 0.82
Methane SCHEMBL11807141 0.82
Methane SCHEMBL19171387 0.82
Methane SCHEMBL7200863 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118048051-A Polymerizable group-containing phthalocyanine dye, and synthetic method and application thereof 大连理工大学 2024-05-17 CN claimed
CN-113087601-B Fischer-Tropsch olefin-based high-carbon ether preparation method and high-carbon ether phase change material 内蒙古伊泰煤基新材料研究院有限公司 2023-12-26 CN claimed
CN-116284782-A Ionic gel with both hydrophobicity and high rebound resilience as well as preparation method and application thereof 南方科技大学 2023-06-23 CN claimed
CN-115895260-A Ionic gel and preparation method and application thereof 南方科技大学 2023-04-04 CN claimed
CN-113061240-B Precursor and preparation method thereof, super-amphiphobic coating material and preparation method thereof, and super-amphiphobic coating 天津承科翊华科技有限公司 2022-11-11 CN claimed
CN-113817011-A Preparation method of 3-site enol ether or ester protected androstane 16 alpha-methyl 天津天药药业股份有限公司 2021-12-21 CN claimed
CN-113817015-A Preparation method of 3-diol protected androstane 16 alpha-methyl 天津天药药业股份有限公司 2021-12-21 CN claimed
CN-113817016-A Preparation method of 3-amino protected androstane 16 alpha-methyl 天津天药药业股份有限公司 2021-12-21 CN claimed
CN-113087601-A High-carbon ether preparation method based on Fischer-Tropsch olefins and high-carbon ether phase change material 内蒙古伊泰煤基新材料研究院有限公司 2021-07-09 CN claimed
CN-113061240-A Precursor and preparation method thereof, super-amphiphobic coating material and preparation method thereof, and super-amphiphobic coating 天津承科翊华科技有限公司 2021-07-02 CN claimed
CN-103254102-A Method for purifying acrylamide alkyl sulfonic acid HEFEI ALL PLUS ENVIRONMENTAL PROT TECHNOLOGY CO LTD 2013-08-21 CN claimed
CN-102858761-A Cyclic carbonyl compounds with pendant pentafluorophenyl carbonate groups, preparations thereof, and polymers therefrom IBM 2013-01-02 CN claimed
CN-1909906-A 2,6-disubstituted piperidines as modulators of chemokine receptor activity MERCK & CO INC (US) 2007-02-07 CN claimed
US-20050238594-A1 Block ethylenic copolymers comprising a vinyllactam block, cosmetic or pharmaceutical compositions comprising them and cosmetic use of these copolymers L'OREAL S.A. (FR) 2005-10-27 US claimed
CN-1224022-A New process for extracting tea saponin XIERUI SCI & TRADE CO LTD CHON (CN) 1999-07-28 CN claimed
US-5104492-A Solvent extraction, dewatering recycling of solvent and precipitation mother liquor reduces waste products THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1992-04-14 US claimed
US-4762875-A Water based printing inks for plastic and metal surfaces GOLD MARVIN H (US) 1988-08-09 US claimed
US-4762865-A Epoxy coatings for computer hard disks and metal coil decoration and protection GOLD MARVIN H (US) 1988-08-09 US claimed
US-4652388-A WATER BASED DISPERSION; ADHESIVE PLASTICIZER AND POLYMER GOLD MARVIN H (US) 1987-03-24 US claimed
US-4207400-A ZINC, IRON, MAGNESIUM, CALCIUM, BARIUM MONSANTO COMPANY (US) 1980-06-10 US claimed