Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10212137 | 0.79 | AKR1B1 (0.47) | THRBPTGS2PTGS1CYP2C9MRGPRX4 | |
| SCHEMBL508558 | 0.78 | PTGS2 (0.47) | POLBPTGS2PTGS1CYP2C9RXRA | |
| SCHEMBL19475238 | 0.76 | THRA (0.39) | THRBALDH1A1PTGS2PTGS1CYP2C9 | |
| SCHEMBL15728088 | 0.73 | RXRA (0.51) | THRBALDH1A1POLBGAAPTGS1 | |
| SCHEMBL9658959 | 0.73 | AKR1B1 (0.46) | THRBAKR1C3AKR1C2AURKATHRA | |
| SCHEMBL25460728 | 0.71 | FFAR4 (0.49) | THRBMRGPRX4FFAR1FFAR4THRA | |
| SCHEMBL30057748 | 0.71 | FFAR4 (0.49) | THRBMRGPRX4FFAR1FFAR4THRA | |
| SCHEMBL18528855 | 0.70 | PKM (0.61) | THRBALDH1A1POLBGAA | |
| SCHEMBL30799387 | 0.70 | AKR1B1 (0.38) | FFAR4EPHX2RXRARXRBRXRG | |
| SCHEMBL27034924 | 0.70 | AKR1B1 (0.38) | FFAR4EPHX2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507537-B2 | Trifluromethoxyphenyl-substituted tetramic acid derivatives pesticides and/or herbicides | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | BAYER CROPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2121597-B1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2121597-A1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008067873-A1 | TRIFLUOROMETHOXYPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES AS PESTICIDES AND/OR HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015807-A1 | Trifluromethoxyphenyl-Substituted Tetramic Acid Derivatives Pesticides and/or Herbicides | DDT, PTPRG, SLC1A5 | THRB 822/4885ALDH1A1 3990/4885POLB 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.