Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509824 | 0.79 | HSD17B10 (0.54) | PTGS1HSD17B10POLBCYP2C9KDM4E | |
| SCHEMBL340962 | 0.78 | THRB (0.43) | PTGS2PTGS1POLBCYP2C9RXRA | |
| SCHEMBL10212137 | 0.78 | AKR1B1 (0.47) | PTGS2PTGS1PTGDR2CYP2C9MAPT | |
| SCHEMBL19475238 | 0.78 | THRA (0.39) | PTGS2PTGS1CYP2C9 | |
| SCHEMBL509209 | 0.77 | RXRA (0.49) | PTGDR2RXRARXRBRXRG | |
| SCHEMBL509065 | 0.76 | RXRA (0.40) | HSD17B10POLBKDM4EMAPTRXRA | |
| SCHEMBL19475583 | 0.74 | AGBL2 (0.41) | HSD17B10PTGDR2POLBKDM4EMAPT | |
| SCHEMBL510120 | 0.72 | MAPT (0.46) | PTGS2PTGDR2POLBKDM4EMAPT | |
| SCHEMBL1561518 | 0.72 | FFAR4 (0.51) | HSD17B10PTGDR2CYP2C9 | |
| SCHEMBL15728088 | 0.72 | RXRA (0.51) | PTGS1HSD17B10POLBKDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507410-B2 | Pyridazinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8470738-B2 | Pyridazinone compound and herbicide containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| CN-101861306-B | 4-phenyl-5-hydroxy-3(2H)-pyridazinone derivatives herbicides | SUMITOMO CHEMICAL CO | 2013-02-06 | — | — | CN | disclosed |
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-02-02 | — | — | US | disclosed |
| EP-2188264-B1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-03-23 | — | — | EP | disclosed |
| CN-101861306-A | 4-phenyl-5-hydroxy-3(2H)-pyridazinone derivatives as herbicides | SUMITOMO CHEMICAL CO | 2010-10-13 | — | — | CN | disclosed |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028803-A1 | PYRIDAZINONE COMPOUND AND USE THEREOF | C5, C1S, WEE1 | PTGS2 2562/4885PTGS1 1886/4885HSD17B10 1169/4885 |
| US-20100216642-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE CONTAINING THE SAME | WEE1, WEE2, CBR3 | PTGS2 2045/4885PTGS1 1595/4885HSD17B10 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.