Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402515 | 0.77 | OPRM1 (0.44) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL3301596 | 0.74 | ALDH1A1 (0.61) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL2037132 | 0.74 | ALDH1A1 (0.51) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3409354 | 0.73 | HDAC1 (0.45) | KMT2AMEN1LMNASMN1; SMN2GAA | |
| SCHEMBL3404199 | 0.73 | MEN1 (0.49) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL12727851 | 0.73 | GAA (0.44) | LMNASMN1; SMN2GAAKLK7ALDH1A1 | |
| SCHEMBL2346348 | 0.71 | ALDH1A1 (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL3407629 | 0.71 | KDM1A (0.46) | KMT2AMEN1LMNAGAAMAPT | |
| SCHEMBL1575208 | 0.71 | GRIN2B (0.54) | KMT2ALMNASMN1; SMN2GAANPC1 | |
| SCHEMBL1574710 | 0.69 | GRIN2B (0.52) | KMT2ALMNASMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | claimed |
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |