Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402515 | 0.81 | OPRM1 (0.44) | TAAR1HTTKMT2ALMNAGAA | |
| SCHEMBL3409354 | 0.77 | HDAC1 (0.45) | KDM1AHTTKMT2ALMNAGAA | |
| SCHEMBL3404199 | 0.77 | MEN1 (0.49) | KDM1AHTTKMT2ALMNAALDH1A1 | |
| SCHEMBL2037132 | 0.75 | ALDH1A1 (0.51) | TAAR1HTTKMT2ALMNAPOLB | |
| SCHEMBL2346348 | 0.72 | ALDH1A1 (0.47) | TAAR1HTTKMT2ALMNAALOX15 | |
| SCHEMBL2340823 | 0.72 | ALDH1A1 (0.43) | TAAR1HTTKMT2APOLBALDH1A1 | |
| SCHEMBL3410307 | 0.71 | KMT2A (0.46) | KMT2ALMNAGAAMAPTALDH1A1 | |
| SCHEMBL3410387 | 0.69 | LMNA (0.40) | HTTKMT2ALMNAGAAPOLB | |
| SCHEMBL9956411 | 0.69 | NPSR1 (0.45) | KDM1AHTTKMT2APOLBALOX15 | |
| SCHEMBL15272208 | 0.67 | MEN1 (0.55) | KDM1AKMT2ALMNAGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | claimed |
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |