Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402515 | 0.83 | OPRM1 (0.44) | MEN1KMT2AHTTRAB9ALMNA | |
| SCHEMBL3409354 | 0.79 | HDAC1 (0.45) | MEN1KMT2AKDM1AHTTCYP3A4 | |
| SCHEMBL2037132 | 0.77 | ALDH1A1 (0.51) | MEN1KMT2AHTTRAB9ANPSR1 | |
| SCHEMBL3407629 | 0.77 | KDM1A (0.46) | MEN1KMT2AKDM1AHTTLMNA | |
| SCHEMBL2346348 | 0.74 | ALDH1A1 (0.47) | MEN1KMT2AHTTRAB9AHPGD | |
| SCHEMBL14506227 | 0.74 | KMT2A (0.44) | MEN1KMT2AKDM1AHTTRAB9A | |
| SCHEMBL2340823 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AHTTRAB9AKDM4E | |
| SCHEMBL3410307 | 0.73 | KMT2A (0.46) | MEN1KMT2ARAB9ALMNANPC1 | |
| SCHEMBL13603925 | 0.72 | LMNA (0.51) | MEN1KMT2AHTTRAB9AHPGD | |
| SCHEMBL3410387 | 0.71 | LMNA (0.40) | KMT2AHTTCYP2C19LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | claimed |
| EP-2177502-A1 | Compounds and their use | Oryzon Genomics, S.A. (ES) | 2010-04-21 | — | — | EP | disclosed |