Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 6/20 | 0.34 |
| ▸ | CHUK | O15111 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206215 | 0.84 | DPP4 (0.39) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL29173579 | 0.84 | DPP4 (0.39) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL31179352 | 0.84 | MAPT (0.40) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL29173645 | 0.84 | DPP4 (0.39) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL30206061 | 0.84 | DPP4 (0.39) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL30206029 | 0.74 | IKBKB (0.33) | ADORA2AADORA1IKBKBCHUKLMNA | |
| SCHEMBL18232336 | 0.72 | CDK1 (0.35) | ADORA2AADORA1LMNAGDADPP4 | |
| SCHEMBL30377425 | 0.72 | CDK1 (0.35) | ADORA2AADORA1LMNAGDADPP4 | |
| SCHEMBL25241852 | 0.72 | CDK1 (0.35) | ADORA2AADORA1LMNAGDADPP4 | |
| SCHEMBL18787933 | 0.72 | AHCYL1 (0.31) | ADORA2AADORA1GDAPIK3CDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131344-A1 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHODS OF MAKING SAME | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| US-20130131344-A1 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHODS OF MAKING SAME | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| WO-2013005157-A1 | SULFONE DERIVATIVES AND THEIR USE AS PKM2 MODULATORS FOR THE TREATMENT OF CANCER | LUPIN LIMITED (IN) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013005157-A1 | SULFONE DERIVATIVES AND THEIR USE AS PKM2 MODULATORS FOR THE TREATMENT OF CANCER | LUPIN LIMITED (IN) | 2013-01-10 | — | — | WO | disclosed |
| US-20120259117-A1 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120259117-A1 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-10-11 | — | — | US | disclosed |
| WO-2011146155-A9 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHOD OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011146155-A2 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHOD OF MAKING SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259117-A1 | ORGANO-METALLIC FRAMEWORKS AND METHODS OF MAKING SAME | HNRNPF, EPCAM, YTHDF2 | ADORA2A 3216/4885ADORA1 4425/4885IKBKB 2376/4885 |
| US-20130131344-A1 | ORGANO-METALLIC FRAMEWORKS DERIVED FROM CARBENOPHILIC METALS AND METHODS OF MAKING SAME | CA6, GZMB, PMS2 | ADORA2A 2132/4885ADORA1 3748/4885IKBKB 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.