Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 13/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412133 | 0.75 | KEAP1 (0.46) | CYP2C19MAPTKMT2AMEN1GAA | |
| SCHEMBL3414271 | 0.71 | MAPT (0.46) | MAPTKMT2AMEN1KDM4EALPL | |
| SCHEMBL3405825 | 0.70 | MAPT (0.55) | MAPTKMT2AMEN1KDM4EALPL | |
| SCHEMBL2637571 | 0.69 | ALDH1A1 (0.50) | CYP1A2CYP3A4CYP2C19MAPTKMT2A | |
| SCHEMBL2637523 | 0.67 | FFAR4 (0.44) | CYP1A2CYP3A4CYP2C19MAPTKMT2A | |
| SCHEMBL3409206 | 0.67 | MAPT (0.47) | MAPTKMT2AMEN1KDM4EALPL | |
| SCHEMBL3409245 | 0.67 | MEN1 (0.50) | MAPTKMT2AMEN1KDM4EALPL | |
| SCHEMBL3411760 | 0.66 | MAPT (0.59) | CYP1A2CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL3411499 | 0.65 | MAPT (0.47) | CYP1A2CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL2637663 | 0.65 | PGR (0.42) | CYP1A2CYP3A4CYP2C19MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2264035-A1 | Glycine B antagonists | Merz Pharma GmbH & Co. KGaA (DE) | 2010-12-22 | — | — | EP | claimed |
| EP-2264035-A1 | Glycine B antagonists | Merz Pharma GmbH & Co. KGaA (DE) | 2010-12-22 | — | — | EP | disclosed |