Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22413722 | 0.80 | ALDH1A1 (0.39) | LMNACA12CA1CA2CA9 | |
| SCHEMBL5962469 | 0.79 | HDAC6 (0.36) | — | |
| SCHEMBL21081853 | 0.77 | MEN1 (0.37) | LMNACA12CA1CA2CA9 | |
| SCHEMBL342653 | 0.76 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL24439349 | 0.75 | LMNA (0.41) | LMNACA12CA1CA2CA9 | |
| SCHEMBL342403 | 0.74 | CHRM1 (0.35) | — | |
| SCHEMBL8888937 | 0.71 | — | — | |
| SCHEMBL10292049 | 0.71 | ALDH1A1 (0.46) | LMNACA12CA1CA2CA9 | |
| SCHEMBL8648874 | 0.70 | CA12 (0.44) | LMNACA12CA1CA2CA9 | |
| SCHEMBL510818 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | claimed |
| CN-103261145-B | There is the amine of secondary aliphatic amino group | SIKA TECHNOLOGY AG (CH) | 2016-04-13 | — | — | CN | claimed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | claimed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | claimed |
| CN-103261145-A | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | claimed |
| US-8157950-B2 | Aldimine and composition containing aldimine | SIKA TECHNOLOGY AG (CH) | 2012-04-17 | — | — | US | claimed |
| US-20110253309-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-10-20 | — | — | US | claimed |
| EP-2194082-B1 | Aldimine and composition comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2011-09-07 | — | — | EP | claimed |
| EP-2194082-A1 | Aldimine and composition comprising aldimine | Sika Technology AG (CH) | 2010-06-09 | — | — | EP | claimed |
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| EP-2414418-B1 | COMPOSITION CURABLE IN TWO STAGES COMPRISING A SURFACE DEACTIVATED POLYISOCYANATE | SIKA TECH AG (CH) | 2017-08-09 | — | — | EP | disclosed |
| CN-103261145-B | There is the amine of secondary aliphatic amino group | SIKA TECHNOLOGY AG (CH) | 2016-04-13 | — | — | CN | disclosed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | disclosed |
| US-9011630-B2 | Hot curing or heat-activated composition containing a surface-deactivated polyisocyanate | SIKA TECHNOLOGIES AG (CH) | 2015-04-21 | — | — | US | disclosed |
| WO-2010112536-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| EP-2236535-A1 | Humidity curing polyurethane composition being accelerated by influence of heat | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236533-A1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236534-A1 | Composition curable in two stages comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2010063741-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-06-10 | — | — | WO | disclosed |
| EP-2194082-A1 | Aldimine and composition comprising aldimine | Sika Technology AG (CH) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | AAAS, PNMT, PARG | PKM 2812/4885LMNA 1183/4885CA12 3833/4885 |
| US-20110253309-A1 | ALDIMINE AND COMPOSITION CONTAINING ALDIMINE | ALDH7A1, ALDH3A1, ADH5 | PKM 105/4885LMNA 343/4885CA12 1993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.