Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412727 | 0.87 | F7 (0.58) | DAOFLT3HRH4F7F3 | |
| SCHEMBL27528325 | 0.85 | ALOX15 (0.55) | ALOX15DAOPDGFRBFLT3HRH4 | |
| SCHEMBL3381701 | 0.80 | HRH4 (0.43) | HRH4KDM4E | |
| SCHEMBL3411403 | 0.80 | DAO (0.50) | DAOPDGFRBFLT3KDM4EMEN1 | |
| SCHEMBL3414920 | 0.80 | DAO (0.50) | DAOFLT3KDM4ELMNAHPGD | |
| SCHEMBL1122030 | 0.79 | ALOX15 (0.53) | ALOX15DAOPDGFRBFLT3 | |
| SCHEMBL3420585 | 0.78 | FLT3 (0.54) | ALOX15PDGFRBFLT3HRH4KDM4E | |
| SCHEMBL1833251 | 0.77 | KDM4E (0.55) | DAOPDGFRBFLT3KDM4ELMNA | |
| SCHEMBL6950242 | 0.75 | DAO (0.49) | ALOX15DAOPDGFRBFLT3HRH4 | |
| SCHEMBL10506377 | 0.75 | ALOX15 (0.48) | ALOX15DAOPDGFRBFLT3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |