Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.60 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394289 | 0.82 | KCNMA1 (0.79) | KCNMA1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28069367 | 0.81 | KCNMA1 (0.78) | KCNMA1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL1963164 | 0.80 | KMT2A (0.65) | KCNMA1CRHBPCRHR2CYP1A2CYP3A4 | |
| SCHEMBL3414932 | 0.80 | NPC1 (0.63) | ABCG2KMT2AMEN1POLBGAA | |
| SCHEMBL7161488 | 0.80 | CRHBP (0.68) | KCNMA1CRHBPCRHR2CYP1A2CYP3A4 | |
| SCHEMBL29506396 | 0.79 | GPR35 (0.64) | KCNMA1CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL312392 | 0.79 | GPR35 (0.64) | KCNMA1CRHBPCRHR2KMT2AMEN1 | |
| SCHEMBL7722700 | 0.79 | ALDH1A1 (0.68) | KCNMA1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4958325 | 0.79 | KCNMA1 (0.64) | KCNMA1CRHBPCRHR2CYP1A2CYP3A4 | |
| SCHEMBL4958316 | 0.79 | KCNMA1 (0.64) | KCNMA1CRHBPCRHR2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |
| WO-2010002075-A1 | METHODS FOR PREPARING AMIDE DERIVATIVES | PHARMACOSTECH CO., LTD. (KR) | 2010-01-07 | — | — | WO | disclosed |