SCHEMBL341538

SCHEMBL341538

COc1ccc(N(CC(=O)O)c2ccccc2)c(C(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 14/20 0.47
NFE2L2 Q16236 14/20 0.47
MTNR1A P48039 3/20 0.45
MTNR1B P49286 3/20 0.45
KDM4E B2RXH2 1/20 0.45
POLB P06746 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9536183 0.83 MTNR1A (0.43) MTNR1AMTNR1BKDM4EPOLBSMN1; SMN2
SCHEMBL341927 0.81 ALDH1A1 (0.45) MTNR1AMTNR1BKDM4EPOLBSMN1; SMN2
SCHEMBL10654450 0.81 MTNR1A (0.44) KEAP1NFE2L2MTNR1AMTNR1BKDM4E
SCHEMBL5694511 0.80 SMN1; SMN2 (0.49) KEAP1NFE2L2KDM4EPOLBSMN1; SMN2
SCHEMBL28676841 0.80 KDM4E (0.49) MTNR1AMTNR1BKDM4EPOLBSMN1; SMN2
SCHEMBL2485731 0.79 MTNR1A (0.60) KEAP1NFE2L2MTNR1AMTNR1BKDM4E
SCHEMBL10464436 0.79 KEAP1 (0.44) KEAP1NFE2L2MTNR1AMTNR1BKDM4E
Hydrochloric Acid SCHEMBL2483359 0.78 MTNR1A (0.58) KEAP1NFE2L2MTNR1AMTNR1BKDM4E
SCHEMBL11165063 0.75 SMN1; SMN2 (0.56) KDM4EPOLBSMN1; SMN2AKR1C3AKR1C2
SCHEMBL9535069 0.74 MTNR1A (0.43) KEAP1NFE2L2MTNR1AMTNR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-1431032-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-09 EP disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20120015295-A1 INFRARED-SENSITIVE COMPOSITION FOR PRINTING PLATE PRECURSORS CITICORP NORTH AMERICA, INC., AS AGENT 2012-01-19 US disclosed
EP-1862301-B1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2011-09-28 EP disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-20030003399-A1 Infrared radiation absorbers, radical producers of polyhaloalkyl -substituted compounds, polycarboxylic acids, and leuco dyes; printing plate precursors KODAK AMERICAS LTD. 2003-01-02 US disclosed
US-20020197564-A1 Stabilized infrared-sensitive polymerizable systems KODAK AMERICAS LTD. 2002-12-26 US disclosed
EP-1249343-A2 Thermal initiator system using leuco dyes and polyhalogene compounds Kodak Polychrome Graphics GmbH (DE) 2002-10-16 EP disclosed
US-6309792-B1 MIXTURE OF ABSORBER, FREE RADICAL FORMING COMPOUND AND POLYCARBOXYLIC ACID KODAK POLYCHROME GRAPHICS LLC 2001-10-30 US disclosed
EP-1079972-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS Kodak Polychrome Graphics Company Ltd. (US) 2001-03-07 EP disclosed
WO-2000048836-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2000-08-24 WO disclosed
EP-0092380-B1 ANTIALLERGIC 4H-FURO(3,2-B)INDOLES AND THEIR PRODUCTION WARNER-LAMBERT COMPANY (US) 1988-01-20 EP disclosed
US-4596814-A Antiallergens WARNER-LAMBERT COMPANY (US) 1986-06-24 US disclosed
US-4503236-A Antiallergic 4Hfuro[3,2-b]indoles WARNER-LAMBERT COMPANY (US) 1985-03-05 US disclosed
EP-0092380-A2 Antiallergic 4H-furo(3,2-b)indoles and their production WARNER-LAMBERT COMPANY (US) 1983-10-26 EP disclosed