SCHEMBL3415549

SCHEMBL3415549

CN(C)CCNc1cccc2c1C(=O)c1cccc(NCCO)c1C2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NSD2 O96028 1/20 0.62
▸ FGB P02675 1/20 0.62
▸ MMP14 P50281 1/20 0.62
▸ MAPT P10636 5/20 0.60
▸ SMN1; SMN2 Q16637 4/20 0.60
▸ MAPK1 P28482 4/20 0.60
▸ KMT2A Q03164 4/20 0.60
▸ MEN1 O00255 3/20 0.60
▸ ALDH1A1 P00352 3/20 0.60
▸ RAD52 P43351 3/20 0.60
▸ HTT P42858 2/20 0.60
▸ BLM P54132 2/20 0.60
▸ EGFR P00533 2/20 0.60
▸ L3MBTL1 Q9Y468 2/20 0.60
▸ POLB P06746 2/20 0.60
▸ NPSR1 Q6W5P4 2/20 0.60
▸ LMNA P02545 1/20 0.60
▸ RECQL P46063 1/20 0.60
▸ TERT O14746 4/20 0.58
▸ TOP2B Q02880 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3418821 0.93 TERT (0.61) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL31218585 0.88 MAPT (0.63) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL3418752 0.88 MAPT (0.63) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL13434540 0.88 TERT (0.57) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL3416154 0.88 TERT (0.62) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL9357997 0.88 NSD2 (0.77) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL13434544 0.87 SMN1; SMN2 (0.59) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL14882640 0.87 TERT (0.56) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL3420790 0.87 SMN1; SMN2 (0.64) NSD2FGBMMP14MAPTSMN1; SMN2
SCHEMBL5086164 0.86 TERT (0.56) NSD2FGBMMP14MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 — — US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 — — US disclosed
US-9334281-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2016-05-10 — — US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-8715944-B2 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. (US) 2014-05-06 — — US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
WO-2010028349-A2 FLUOROCHROMES FOR ORGANELLE TRACING AND MULTI-COLOR IMAGING ENZO LIFE SCIENCES, INC. (US) 2010-03-11 — — WO disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging ENZO LIFE SCIENCES, INC. 2010-03-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062429-A1 Fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NDC1 NSD2 3033/4885FGB 3643/4885MMP14 4644/4885
US-20100062460-A1 Novel fluorochromes for organelle tracing and multi-color imaging MFN2, TFEB, NUMA1 NSD2 3089/4885FGB 3962/4885MMP14 4681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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