SCHEMBL341836

SCHEMBL341836

NCCc1ccccc1B(O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.47
TRPV6 Q9H1D0 3/20 0.46
ORAI1 Q96D31 2/20 0.46
ORAI2 Q96SN7 2/20 0.46
ORAI3 Q9BRQ5 2/20 0.46
PCSK9 Q8NBP7 1/20 0.46
HTR2A P28223 2/20 0.44
HRH1 P35367 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
CYP2A6 P11509 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
HMGB1 P09429 1/20 0.39
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
ENPP2 Q13822 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27541809 0.96 TAAR1 (0.44) TAAR1TRPV6ORAI1ORAI2ORAI3
SCHEMBL1469675 0.85 TRPV6 (0.50) TAAR1TRPV6ORAI1ORAI2ORAI3
SCHEMBL6701793 0.80 LIPG (0.60) TAAR1HTR2AHRH1LIPGCYP2A6
SCHEMBL12271157 0.77 TRPV6 (0.50) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL3274578 0.77 TRPV6 (0.50) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL2408016 0.76 TRPV6 (0.41) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL2400530 0.76 TRPV6 (0.48) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL2405808 0.75 TRPV6 (0.72) TRPV6ORAI1ORAI2ORAI3PCSK9
SCHEMBL30966487 0.73 HPGD (0.66) TAAR1TRPV6ORAI1ORAI2ORAI3
SCHEMBL28932400 0.71 TAAR1 (0.44) TAAR1HTR2AHRH1LIPGHMGB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3117212-B1 METHOD OF STUDYING ABCG2 PROTEIN ACTIVITY AND USE OF 2-AMINOETHYL DIPHENYLBORINATE UNIV LODZKI (PL) 2018-05-30 EP claimed
EP-3117212-A1 METHOD OF STUDYING ABCG2 PROTEIN ACTIVITY AND USE OF 2-AMINOETHYL DIPHENYLBORINATE Uniwersytet Lodzki (PL) 2017-01-18 EP claimed
WO-2015137832-A1 METHOD OF STUDYING ABCG2 PROTEIN ACTIVITY AND USE OF 2-AMINOETHYL DIPHENYLBORINATE Uniwersytet Łódzki (PL) 2015-09-17 WO claimed
EP-2102653-B9 METHOD AND KIT FOR TESTING WHETHER A SPECIFIC PLANT HAS BEEN EXPOSED TO A SPECIFIC PESTICIDE UNIV AARHUS (DK) 2014-12-31 EP claimed
EP-2102653-B1 METHOD AND KIT FOR TESTING WHETHER A SPECIFIC PLANT HAS BEEN EXPOSED TO A SPECIFIC PESTICIDE UNIV AARHUS (DK) 2014-08-13 EP claimed
EP-2102654-B1 METHOD AND KIT FOR DETECTING HERBICIDE RESISTANCE IN PLANTS UNIV AARHUS (DK) 2014-08-13 EP claimed
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms AARHUS UNIVERSITET (DK) 2010-06-17 US claimed
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms AARHUS UNIVERSITET (DK) 2010-02-25 US claimed
EP-2102654-A1 METHOD AND KIT FOR DETECTING RESISTANCE IN LIVING ORGANISMS Aarhus Universitet (DK) 2009-09-23 EP claimed
EP-2102653-A1 A METHOD AND KIT FOR TESTING STRESS EFFECTS IN LIVING ORGANISM Aarhus Universitet (DK) 2009-09-23 EP claimed
WO-2008080409-A1 A METHOD AND KIT FOR TESTING STRESS EFFECTS IN LIVING ORGANISM AARHUS UNIVERSITET (DK) 2008-07-10 WO claimed
WO-2008080410-A1 METHOD AND KIT FOR DETECTING RESISTANCE IN LIVING ORGANISMS AARHUS UNIVERSITET (DK) 2008-07-10 WO claimed
US-12435061-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2025-10-07 US disclosed
US-20250276993-A1 PSEUDO-DISACCHARIDE COMPOUNDS UNIVERSITEIT LEIDEN (NL) 2025-09-04 US disclosed
EP-4574822-A2 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2025-06-25 EP disclosed
EP-4514813-A1 PSEUDO-DISACCHARIDE COMPOUNDS Universiteit Leiden (NL) 2025-03-05 EP disclosed
US-6989162-B2 Hepatoprotective agent of plant origin and a process thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2006-01-24 US disclosed
EP-1582250-A2 Absorbent with improved ocidation resistance and process for deacidifying fluid fluxes BASF AKTIENGESELLSCHAFT (DE) 2005-10-05 EP disclosed
WO-2004087184-A1 ISOLATION OF THE HEPATOPROTECTIVE AGENT ACTEOSIDE FROM COLERBROKEA OPPOSITIFOLIA COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-10-14 WO disclosed
US-20040192619-A1 Hepatoprotective agent of plant origin and a process thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435061-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 TAAR1 4437/4885TRPV6 1250/4885ORAI1 3216/4885
US-20100047176-A1 Method and Kit for Testing Stress Effects in Living Organisms DDT, ACHE, WEE1 TAAR1 3578/4885TRPV6 2608/4885ORAI1 4835/4885
US-20250276993-A1 PSEUDO-DISACCHARIDE COMPOUNDS HPSE, HEXD, HEXA TAAR1 4458/4885TRPV6 1966/4885ORAI1 4860/4885
US-20100150842-A1 Method and Kit for Detecting Resistance in Living Organisms DDT, NOTUM, ACHE TAAR1 2943/4885TRPV6 3175/4885ORAI1 4836/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.