Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505329 | 0.83 | ALDH1A1 (0.38) | TDP1KDM4EALOX15ALDH1A1MEN1 | |
| SCHEMBL23201906 | 0.83 | ALDH1A1 (0.38) | TDP1KDM4EALOX15ALDH1A1MEN1 | |
| SCHEMBL26105239 | 0.81 | ALDH1A1 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL26107197 | 0.81 | ALDH1A1 (0.37) | TDP1ALDH1A1 | |
| SCHEMBL175747 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL429048 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL67368 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL27709276 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL65674 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM | |
| SCHEMBL11895837 | 0.81 | TDP1 (0.50) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058834-A1 | Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter | MONSANTO TECHNOLOGY LLC | 2002-05-16 | — | — | US | claimed |
| WO-2001092208-A1 | METAL-CATALYSED CARBOXYMETHYLATION IN THE PRESENCE OF A PROMOTER | MONSANTO TECHNOLOGY LLC (US) | 2001-12-06 | — | — | WO | claimed |
| US-6153753-A | CATALYTIC CARBOXYMETHYLATION OF A CARBAMOYL COMPOUND BY PREMIXING THE CARBAMOYL COMPOUND AND THE CARBOXYMETHYLATION CATALYST PRECURSOR FIRST, THEN ADDING THE WATER AND ALDEHYDE; FORMING N-(PHOSPHONOMETHYL)GLYCINE HERBICIDE OR PESTICIDE | MONSANTO COMPANY (US) | 2000-11-28 | — | — | US | claimed |
| US-5068404-A | Heating aqueous solution of di- or tri-alkali metal salt of N-alkyl-N-phosphonomethylglycine | MONSANTO COMPANY (US) | 1991-11-26 | — | — | US | claimed |
| EP-0449987-A1 | PROCESS FOR THE PREPARATION OF N-PHOSPHONOMETHYLGLYCINE | MONSANTO COMPANY (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990006929-A1 | PROCESS FOR THE PREPARATION OF N-PHOSPHONOMETHYLGLYCINE | MONSANTO COMPANY (US) | 1990-06-28 | — | — | WO | claimed |
| CN-1004696-B | Thermal dealkylation of N-alkyl-N-phosphonomethylglycine | 孟山都公司 | 1989-07-05 | — | — | CN | claimed |
| EP-0187633-B1 | THERMAL DEALKYLATION OF N-ALKYL N-PHOSPHONOMETHYLGLYCINE | Monsanto Company (US) | 1989-03-01 | — | — | EP | claimed |
| US-4684483-A | FROM GLYOXAL, AMINE, SULFUR DIOXIDE | MONSANTO COMPANY (US) | 1987-08-04 | — | — | US | claimed |
| CN-85109393-A | The hot dealkylation reaction of N-alkyl-N phosphonomethylglycine | — | 1986-12-03 | — | — | CN | claimed |
| EP-0187633-A1 | Thermal dealkylation of n-alkyl n-phosphonomethylglycine | Monsanto Company (US) | 1986-07-16 | — | — | EP | claimed |
| EP-1125634-B1 | Shaped fixed bed Raney-Cu catalyst | EVONIK DEGUSSA GMBH (DE) | 2010-12-08 | — | — | EP | disclosed |
| US-7632967-B2 | Raney copper | DEGUSSA AG (DE) | 2009-12-15 | — | — | US | disclosed |
| CN-101530804-A | Skeletal copper | EVONIK DEGUSSA CO LTD | 2009-09-16 | — | — | CN | disclosed |
| US-20070270306-A1 | RANEY COPPER | EVONIK DEGUSSA GMBH (DE) | 2007-11-22 | — | — | US | disclosed |
| US-4650613-A | Process for preparing N-phosphonomethylglycine and derivatives | MONSANTO COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| CN-85109393-A | The hot dealkylation reaction of N-alkyl-N phosphonomethylglycine | — | 1986-12-03 | — | — | CN | disclosed |
| EP-0187633-A1 | Thermal dealkylation of n-alkyl n-phosphonomethylglycine | Monsanto Company (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0187633-A1 | Thermal dealkylation of n-alkyl n-phosphonomethylglycine | Monsanto Company (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0187633-A1 | Thermal dealkylation of n-alkyl n-phosphonomethylglycine | Monsanto Company (US) | 1986-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058834-A1 | Preparation of N-acyl amino carboxylic acids, amino carboxylic acids and their derivatives by metal-catalyzed carboxymethylation in the presence of a promoter | BCAT2, GNMT, BCAT1 | TDP1 4724/4885EYA2 3445/4885APP 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.