Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | F10 | P00742 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192466 | 0.81 | MRGPRX1 (0.74) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL3412013 | 0.79 | MAPT (0.58) | KMT2AALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL5525095 | 0.78 | BCHE (0.64) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL3051565 | 0.78 | LMNA (0.74) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL22387608 | 0.78 | KMT2A (0.56) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL31192444 | 0.77 | BCHE (0.63) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL9416614 | 0.77 | LMNA (0.73) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL2232108 | 0.76 | HSD17B10 (0.60) | KMT2AMAPTKDM4EMEN1GAA | |
| SCHEMBL13958923 | 0.76 | BCHE (0.62) | MRGPRX1F2F10PRSS1F7 | |
| SCHEMBL13973184 | 0.76 | BCHE (0.69) | MRGPRX1F2F10PRSS1F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | CHROMOCELL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2011130707-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011130707-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | TAS2R5, TAS2R20, TAS2R10 | MRGPRX1 623/4885F2 3840/4885F10 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.