SCHEMBL342263

SCHEMBL342263

C=C(C)C(=O)OCCOC(=O)C(O)CC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
TSHR P16473 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.33
MAPT P10636 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.32
LMNA P02545 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL260320 0.86 THRB (0.50) THRBTSHRPOLBAPEX1HTT
Malic Acid SCHEMBL29711798 0.85 THRB (0.54) THRBTSHRSMN1; SMN2POLBAPEX1
Malic Acid SCHEMBL260319 0.81 SMN1; SMN2 (0.48) THRBTSHRSMN1; SMN2POLBAPEX1
SCHEMBL29171115 0.80 POLB (0.45) SMN1; SMN2POLBAPEX1TDP1ALOX15
Malic Acid SCHEMBL9188596 0.80 THRB (0.49) THRBTSHRSMN1; SMN2POLBAPEX1
SCHEMBL261733 0.79 TSHR (0.50) THRBTSHRPOLBAPEX1HTT
Malic Acid SCHEMBL261732 0.79 TSHR (0.46) THRBTSHRSMN1; SMN2POLBAPEX1
SCHEMBL15006942 0.78 THRB (0.63) THRBTSHRSMN1; SMN2POLBAPEX1
SCHEMBL3916030 0.78 THRB (0.68) THRBTSHRSMN1; SMN2POLBAPEX1
SCHEMBL6142874 0.78 THRB (0.74) THRBTSHRSMN1; SMN2POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140192299-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2014-07-10 US claimed
US-8703253-B2 Composition for liquid crystal alignment layer, preparation method of liquid crystal alignment layer using the same, and optical film comprising the liquid crystal alignment layer LG CHEM, LTD. (KR) 2014-04-22 US claimed
US-8329845-B2 Divided redox-curing type composition KURARAY NORITAKE DENTAL INC. (JP) 2012-12-11 US claimed
US-20110051050-A1 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2011-03-03 US claimed
US-20110043731-A1 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2011-02-24 US claimed
WO-2009091227-A2 OPTICAL FILM, PREPARATION METHOD OF THE SAME, AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME LG CHEM, LTD. (KR) 2009-07-23 WO claimed
WO-2009091225-A2 COMPOSITION FOR LIQUID CRYSTAL ALIGNMENT LAYER, PREPARATION METHOD OF LIQUID CRYSTAL ALIGNMENT LAYER USING THE SAME, AND OPTICAL FILM COMPRISING THE LIQUID CRYSTAL ALIGNMENT LAYER LG CHEM, LTD. (KR) 2009-07-23 WO claimed
US-20240199773-A1 COMPOSITION AND METHOD FOR PRODUCING COMPOSITION KANEKA CORPORATION (JP) 2024-06-20 US disclosed
EP-3848418-B1 DENTAL CURABLE COMPOSITION AND METHOD FOR PRODUCING DENTAL CURABLE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2024-05-22 EP disclosed
US-20240139078-A1 DENTAL FILLING KIT KURARAY NORITAKE DENTAL INC. (JP) 2024-05-02 US disclosed
EP-4360609-A1 DENTAL ADHESIVE KIT Kuraray Noritake Dental Inc. (JP) 2024-05-01 EP disclosed
US-20240091107-A1 DENTAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2024-03-21 US disclosed
WO-2024053223-A1 CARIOUS TOOTH STRUCTURE RECOVERY AGENT, AND DENTAL ADHESIVE KIT クラレノリタケデンタル株式会社 2024-03-14 WO disclosed
EP-0712622-B1 Dental composition and kit TOKUYAMA CORP (JP) 1999-09-01 EP disclosed
US-5925690-A UNSATURATED PHOSPHATE AND UNSATURATED POLYCARBOXYLIC ACID MONOMERS; BONDING AND TENSILE STRENGTH TO DENTIN AND ENAMEL TOKUYAMA CORPROATION (JP) 1999-07-20 US disclosed
US-5866631-A POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. TOKUYAMA CORPORATION (JP) 1999-02-02 US disclosed
EP-0886660-A1 PHOTOCURABLE PUTTY FOR REPAIRING SHEET METAL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-12-30 EP disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed
WO-1997033928-A1 PHOTOCURABLE PUTTY FOR REPAIRING SHEET METAL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-18 WO disclosed
EP-0712622-A1 Dental composition and kit TOKUYAMA CORPORATION (JP) 1996-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139078-A1 DENTAL FILLING KIT DHX29, DHX35, DHX15 THRB 4487/4885TSHR 4803/4885SMN1; SMN2 4512/4885
US-20240091107-A1 DENTAL COMPOSITION CCT7, TAS2R42, CCT5 THRB 3006/4885TSHR 3718/4885SMN1; SMN2 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.