SCHEMBL3423630

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28187809	0.82	ALDH1A1 (0.50)	ALDH1A1CYP3A4RECQLCASP1CA2
	Aniline SCHEMBL27974743	0.82	TSHR (0.46)	ALDH1A1CYP3A4CA2CA12CA1
	SCHEMBL7821983	0.76	FBP1 (0.44)	TDP1TSHRLMNAL3MBTL1
	SCHEMBL11095155	0.76	ACHE (0.52)	ALDH1A1CYP3A4TDP1TSHRLMNA
	SCHEMBL11669407	0.76	ALDH1A1 (0.36)	ALDH1A1TSHRLMNAMAPK1L3MBTL1
	SCHEMBL9865775	0.75	ALDH1A1 (0.43)	ALDH1A1CYP3A4RECQLCASP1CA2
	SCHEMBL7521942	0.74	ALDH1A1 (0.50)	ALDH1A1CYP3A4RECQLCA2CA12
	SCHEMBL17935	0.73	ALDH1A1 (0.50)	ALDH1A1TDP1ALOX15LMNAMAPK1
	SCHEMBL28115797	0.73	ALDH1A1 (0.50)	ALDH1A1TDP1ALOX15LMNAMAPK1
	SCHEMBL30996000	0.72	ALDH1A1 (0.35)	ALDH1A1TSHRLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.